PMID- 18774435
OWN - NLM
STAT- MEDLINE
DCOM- 20090112
LR  - 20181201
IS  - 0163-8343 (Print)
IS  - 0163-8343 (Linking)
VI  - 30
IP  - 5
DP  - 2008 Sep-Oct
TI  - Neuroleptic malignant syndrome without fever after addition of oxcarbazepine to 
      long-term treatment with amisulpride.
PG  - 482-4
LID - 10.1016/j.genhosppsych.2008.03.007 [doi]
AB  - OBJECTIVE: Our goal was to report a case of malignant neuroleptic syndrome in a 
      patient administered with both oxcarbazepine (OXCBZ) and amisulpride (AM). 
      METHOD: We present a case of a young man who presented with symptoms of malignant 
      neuroleptic syndrome after progressive titration of OXCBZ (1,200 mg) added to the 
      long-term treatment with AM (800 mg). RESULTS: After discontinuation of AM and 
      administration of dopaminergic drugs, his clinical symptoms improved gradually. 
      CONCLUSION: This case suggests that clinicians should consider the risk of 
      neuroleptic malignant syndrome when OXCBZ is coadministered to patients 
      undergoing long-term treatment with neuroleptics.
FAU - Angelopoulos, Petros
AU  - Angelopoulos P
AD  - General Hospital of Thessaloniki, Greece. petrosangelopoulos@yahoo.gr
FAU - Markopoulou, Maria
AU  - Markopoulou M
FAU - Kyamidis, Kyriakos
AU  - Kyamidis K
FAU - Bobotas, Konstantinos
AU  - Bobotas K
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20080723
PL  - United States
TA  - Gen Hosp Psychiatry
JT  - General hospital psychiatry
JID - 7905527
RN  - 0 (Anticonvulsants)
RN  - 0 (Antipsychotic Agents)
RN  - 33CM23913M (Carbamazepine)
RN  - 7MNE9M8287 (Sulpiride)
RN  - 8110R61I4U (Amisulpride)
RN  - VZI5B1W380 (Oxcarbazepine)
SB  - IM
MH  - Adult
MH  - Amisulpride
MH  - Anticonvulsants/*adverse effects/therapeutic use
MH  - Antipsychotic Agents/*adverse effects/therapeutic use
MH  - Carbamazepine/adverse effects/*analogs & derivatives/therapeutic use
MH  - Chronic Disease
MH  - Drug Therapy, Combination
MH  - Humans
MH  - Male
MH  - Neuroleptic Malignant Syndrome/diagnosis/*etiology
MH  - Oxcarbazepine
MH  - Schizophrenia/*drug therapy
MH  - Sulpiride/adverse effects/*analogs & derivatives/therapeutic use
EDAT- 2008/09/09 09:00
MHDA- 2009/01/13 09:00
CRDT- 2008/09/09 09:00
PHST- 2008/02/26 00:00 [received]
PHST- 2008/03/21 00:00 [revised]
PHST- 2008/03/24 00:00 [accepted]
PHST- 2008/09/09 09:00 [pubmed]
PHST- 2009/01/13 09:00 [medline]
PHST- 2008/09/09 09:00 [entrez]
AID - S0163-8343(08)00043-1 [pii]
AID - 10.1016/j.genhosppsych.2008.03.007 [doi]
PST - ppublish
SO  - Gen Hosp Psychiatry. 2008 Sep-Oct;30(5):482-4. doi: 
      10.1016/j.genhosppsych.2008.03.007. Epub 2008 Jul 23.