PMID- 18778327 OWN - NLM STAT- MEDLINE DCOM- 20090622 LR - 20111117 IS - 1399-0039 (Electronic) IS - 0001-2815 (Linking) VI - 72 IP - 5 DP - 2008 Nov TI - Polymorphism of HLA-DRB1, -DQB1 and -DPB1 genes in Bai ethnic group in southwestern China. PG - 474-7 LID - 10.1111/j.1399-0039.2008.01120.x [doi] AB - In this work, polymorphism of human leukocyte antigen (HLA)-DRB1, -DQB1 and -DPB1 genes was detected using polymerase chain reaction-sequence-based typing method in 128 healthy unrelated volunteers from the Bai ethnic group of Yunnan province of southwest China. Among all the 28 alleles detected for the DRB1 gene, the most common allele was DRB1*120201 with a frequency of 16.41%, followed by DRB1*090102, DRB1*080302, DRB1*1404, DRB1*150101, DRB1*140101 and DRB1*160201, with frequencies of 10.16%, 9.77%, 9.38%, 8.98%, 8.59% and 8.21%, respectively. Among 19 DQB1 alleles detected, the most frequent allele was DQB1*030101/0309 (35.94%), followed by DQB1*050201 (11.33%), DQB1*060101/060103 (10.54%) and DQB1*0401 (10.16%). For the DPB1 locus, the most common alleles were DPB1*0501 (42.19%), DPB1*1301 (13.28%), DPB1*020102 (10.93%) and DPB1*040101 (9.77%). The comparison of HLA class II allele frequencies of Bais with those of other Chinese populations suggested that the Bai ethnic group belonged to the southern group of Chinese. FAU - Hu, W AU - Hu W AD - Key Laboratory of Bioresources Conservation and Utilization and Human Genetics Center, Yunnan University, Kunming, Yunnan, China. FAU - Tang, L AU - Tang L FAU - Wang, J AU - Wang J FAU - Wang, B AU - Wang B FAU - Li, S AU - Li S FAU - Yu, H AU - Yu H FAU - Tang, W AU - Tang W FAU - Li, H AU - Li H FAU - Tan, S AU - Tan S FAU - Shou, W AU - Shou W FAU - Xiao, C AU - Xiao C LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20080905 PL - England TA - Tissue Antigens JT - Tissue antigens JID - 0331072 RN - 0 (HLA-DP Antigens) RN - 0 (HLA-DP beta-Chains) RN - 0 (HLA-DPB1 antigen) RN - 0 (HLA-DQ Antigens) RN - 0 (HLA-DQ beta-Chains) RN - 0 (HLA-DQB1 antigen) RN - 0 (HLA-DR Antigens) RN - 0 (HLA-DRB1 Chains) SB - IM MH - Alleles MH - China MH - *Gene Frequency MH - HLA-DP Antigens/*genetics MH - HLA-DP beta-Chains MH - HLA-DQ Antigens/*genetics MH - HLA-DQ beta-Chains MH - HLA-DR Antigens/*genetics MH - HLA-DRB1 Chains MH - Humans MH - Polymorphism, Genetic EDAT- 2008/09/10 09:00 MHDA- 2009/06/23 09:00 CRDT- 2008/09/10 09:00 PHST- 2008/09/10 09:00 [pubmed] PHST- 2009/06/23 09:00 [medline] PHST- 2008/09/10 09:00 [entrez] AID - TAN1120 [pii] AID - 10.1111/j.1399-0039.2008.01120.x [doi] PST - ppublish SO - Tissue Antigens. 2008 Nov;72(5):474-7. doi: 10.1111/j.1399-0039.2008.01120.x. Epub 2008 Sep 5.