PMID- 18792087 OWN - NLM STAT- MEDLINE DCOM- 20090223 LR - 20211020 IS - 1049-8931 (Print) IS - 1557-0657 (Electronic) IS - 1049-8931 (Linking) VI - 17 IP - 4 DP - 2008 TI - Development of the Bipolar Inventory of Symptoms Scale: concurrent validity, discriminant validity and retest reliability. PG - 198-209 LID - 10.1002/mpr.262 [doi] AB - Scales used in studies of bipolar disorder have generally been standardized with major depressive or hospitalized manic patients. A clinician rated scale based on a semi-structured interview for persons with bipolar disorder, with comprehensive coverage of bipolar symptomatology, is needed. We report concurrent, divergent and convergent psychometric reliability, discriminant validity and relationship to a measure of overall function for a new psychometric rating instrument. A primarily outpatient sample of 224 subjects was assessed using the Bipolar Inventory of Symptoms Scale (BISS). The BISS total score and depression and mania subscales were compared to the Young Mania Rating Scale (YMRS), the Montgomery Asberg Depression Rating Scale (MADRS) and the Global Assessment of Functioning Scale (GAF). Clinical mood states were also compared using the BISS. The BISS scores demonstrated good concurrent validity, with estimates (Pearson correlations) ranging from 0.74 to 0.94 for YMRS and MADRS and test-retest reliability from 0.95 to 0.98. BISS concurrent validity with the GAF was significant for four clinical states, but not mixed states. The BISS discriminated primary bipolar mood states as well as subjects recovered for eight weeks compared to healthy controls. In conclusion, the BISS is a reliable and valid instrument broadly applicable in clinical research to assess the comprehensive domains of bipolar disorder. Future directions include factor analysis and sensitivity to change from treatment studies. FAU - Gonzalez, Jodi M AU - Gonzalez JM AD - Department of Psychiatry, UT Health Science Center, San Antonio, TX 78229, USA. gonzalezjm1@uthscsa.edu FAU - Bowden, Charles L AU - Bowden CL FAU - Katz, Martin M AU - Katz MM FAU - Thompson, Peter AU - Thompson P FAU - Singh, Vivek AU - Singh V FAU - Prihoda, Thomas J AU - Prihoda TJ FAU - Dahl, Martha AU - Dahl M LA - eng PT - Journal Article PT - Validation Study PL - United States TA - Int J Methods Psychiatr Res JT - International journal of methods in psychiatric research JID - 9111433 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Bipolar Disorder/*diagnosis/psychology MH - Depressive Disorder, Major/*diagnosis/psychology MH - Diagnosis, Differential MH - Disability Evaluation MH - Female MH - Humans MH - *Interview, Psychological MH - Male MH - Middle Aged MH - Personality Assessment/*statistics & numerical data MH - Psychiatric Status Rating Scales/statistics & numerical data MH - Psychometrics/statistics & numerical data MH - Reference Values MH - Reproducibility of Results MH - Young Adult PMC - PMC6878587 EDAT- 2008/09/16 09:00 MHDA- 2009/02/24 09:00 PMCR- 2008/09/12 CRDT- 2008/09/16 09:00 PHST- 2008/09/16 09:00 [pubmed] PHST- 2009/02/24 09:00 [medline] PHST- 2008/09/16 09:00 [entrez] PHST- 2008/09/12 00:00 [pmc-release] AID - MPR262 [pii] AID - 10.1002/mpr.262 [doi] PST - ppublish SO - Int J Methods Psychiatr Res. 2008;17(4):198-209. doi: 10.1002/mpr.262.