PMID- 18797371
OWN - NLM
STAT- MEDLINE
DCOM- 20090224
LR  - 20131121
IS  - 1535-1815 (Electronic)
IS  - 0749-5161 (Linking)
VI  - 24
IP  - 9
DP  - 2008 Sep
TI  - Ecstasy (3,4-methylenedioxymethamphetamine)-induced inappropriate antidiuretic 
      hormone secretion.
PG  - 615-7
LID - 10.1097/PEC.0b013e3181850c91 [doi]
AB  - 3,4-Methylenedioxymethamphetamine (MDMA), popularly known as the illicit drug 
      "Ecstasy," is an amphetamine derivative that has become widely abused throughout 
      the United States and other industrialized nations. 
      3,4-Methylenedioxymethamphetamine has an undeserved reputation as a "safe" drug 
      among its users, but MDMA shares the toxicity profile of other amphetamines. Its 
      use may result in lethal cardiovascular, hepatic, metabolic, or neurological 
      toxicity. The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) 
      is a unique toxicity that may occur after isolated MDMA use. Although the 
      phenomenon is well described in adults, reports of MDMA-induced SIADH and 
      symptomatic hyponatremia in children are rare. We describe a 13-year-old girl who 
      experienced MDMA-induced SIADH with symptomatic hyponatremia. Toxicity of MDMA, 
      in particular, the pathophysiology and treatment of MDMA-induced hyponatremia, is 
      discussed.
FAU - Farah, Raymond
AU  - Farah R
AD  - Department of Internal Medicine F, Leumit Health Service, Western Galilee, 
      Nahariya, Israel. Raymond.Farah@naharia.health.gov.il
FAU - Farah, Rola
AU  - Farah R
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Pediatr Emerg Care
JT  - Pediatric emergency care
JID - 8507560
RN  - 0 (Hallucinogens)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - Adolescent
MH  - Female
MH  - Hallucinogens/*toxicity
MH  - Humans
MH  - Inappropriate ADH Syndrome/*chemically induced
MH  - N-Methyl-3,4-methylenedioxyamphetamine/*toxicity
EDAT- 2008/09/18 09:00
MHDA- 2009/02/25 09:00
CRDT- 2008/09/18 09:00
PHST- 2008/09/18 09:00 [pubmed]
PHST- 2009/02/25 09:00 [medline]
PHST- 2008/09/18 09:00 [entrez]
AID - 00006565-200809000-00006 [pii]
AID - 10.1097/PEC.0b013e3181850c91 [doi]
PST - ppublish
SO  - Pediatr Emerg Care. 2008 Sep;24(9):615-7. doi: 10.1097/PEC.0b013e3181850c91.