PMID- 18802312
OWN - NLM
STAT- MEDLINE
DCOM- 20081230
LR  - 20221207
IS  - 1346-9843 (Print)
IS  - 1346-9843 (Linking)
VI  - 72
IP  - 11
DP  - 2008 Nov
TI  - Long-term results of left ventricular reconstructive surgery in patients with 
      ischemic dilated cardiomyopathy: a multicenter study.
PG  - 1730-6
AB  - BACKGROUND: Left ventricular restoration (LVR) is increasingly used for treatment 
      of chronic heart failure following myocardial infarction. The present 
      multi-institutional retrospective study analyzed the long-term efficacy and 
      limitations of LVR. METHODS AND RESULTS: Seventy-two (58 males, mean age 62+/-10) 
      patients who underwent LVR between January 1999 and June 2007 were included. 
      Preoperatively, 50 (68.5%) were in New York Heart Association (NYHA) functional 
      class III or IV. Mean left ventricular end-diastolic and end-systolic volume 
      indexes were 145+/-43 ml/m(2) and 111+/-40 ml/m(2), respectively, and ejection 
      fraction was 25+/-7.4%. Other concomitant operative procedures included coronary 
      artery bypass grafting in 55 (76.4%), and mitral valve procedures in 38 (52.8%). 
      Thirty-day mortality was 2.8%. Actuarial survival at 1, 3, and 5 years was 95.3%, 
      80.45 and 71.0% respectively. Mean ejection fraction significantly improved to 
      39+/-11%, and left ventricular volumes were significantly reduced in the early 
      postoperative period. During a mean of 3.3+/-2.4 years of follow up, these 
      improvements were still significant in the late period. Of the survivors, 90% 
      were in NYHA functional class I or II. CONCLUSION: LVR can be performed with a 
      low operative mortality and provide satisfactory long-term survival by restoring 
      the dilated left ventricle and improving systolic function.
FAU - Takeda, Koji
AU  - Takeda K
AD  - Division of Cardiovascular Surgery, Department of Surgery, Osaka University 
      Graduate School of Medicine, Suita, Japan.
FAU - Matsumiya, Goro
AU  - Matsumiya G
FAU - Sakaguchi, Taichi
AU  - Sakaguchi T
FAU - Matsue, Hajime
AU  - Matsue H
FAU - Masai, Takafumi
AU  - Masai T
FAU - Otake, Shigeaki
AU  - Otake S
FAU - Taniguchi, Kazuhiro
AU  - Taniguchi K
FAU - Sawa, Yoshiki
AU  - Sawa Y
CN  - Osaka Cardiovascular Surgery Research (OSCAR) group
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20080918
PL  - Japan
TA  - Circ J
JT  - Circulation journal : official journal of the Japanese Circulation Society
JID - 101137683
SB  - IM
MH  - Adult
MH  - Aged
MH  - *Cardiac Surgical Procedures
MH  - Cardiomyopathy, Dilated/*mortality/physiopathology/*surgery
MH  - Disease-Free Survival
MH  - Female
MH  - Heart Ventricles/physiopathology/surgery
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Ischemia/*mortality/physiopathology/*surgery
MH  - *Plastic Surgery Procedures
MH  - Recovery of Function
MH  - Retrospective Studies
MH  - Survival Rate
EDAT- 2008/09/20 09:00
MHDA- 2008/12/31 09:00
CRDT- 2008/09/20 09:00
PHST- 2008/09/20 09:00 [pubmed]
PHST- 2008/12/31 09:00 [medline]
PHST- 2008/09/20 09:00 [entrez]
AID - JST.JSTAGE/circj/CJ-08-0328 [pii]
AID - 10.1253/circj.cj-08-0328 [doi]
PST - ppublish
SO  - Circ J. 2008 Nov;72(11):1730-6. doi: 10.1253/circj.cj-08-0328. Epub 2008 Sep 18.