PMID- 18808697
OWN - NLM
STAT- MEDLINE
DCOM- 20081016
LR  - 20240117
IS  - 1532-429X (Electronic)
IS  - 1097-6647 (Print)
IS  - 1097-6647 (Linking)
VI  - 10
IP  - 1
DP  - 2008 Sep 22
TI  - Comparison of cardiovascular magnetic resonance of late gadolinium enhancement 
      and diastolic wall thickness to predict recovery of left ventricular function 
      after coronary artery bypass surgery.
PG  - 41
LID - 10.1186/1532-429X-10-41 [doi]
AB  - BACKGROUND: The objective was to compare the value of late gadolinium enhancement 
      (LGE) and end-diastolic wall thickness (EDWT) assessed by cardiovascular magnetic 
      resonance (CMR) in predicting recovery of left ventricular function after 
      coronary artery bypass surgery (CABG). METHODS: We enrolled patients with 
      coronary artery disease and left ventricular ejection fraction < 45% who were 
      scheduled for CABG. Regional contractility was assessed by cine CMR at baseline 
      and 4 months after CABG. EDWT and LGE were assessed at baseline. Predictors for 
      improvement of regional contractility were analyzed. RESULTS: We studied 46 men 
      and 4 women with an average age of 61 years. Baseline left ventricular ejection 
      fraction was 37 +/- 13%. A total of 2,020 myocardial segments were analyzed. 
      Abnormal wall motion and the LGE area were detected in 1,446 segments (71.6%) and 
      1,196 segments (59.2%) respectively. Wall motion improvement was demonstrated in 
      481 of 1,227 segments (39.2%) that initially had wall motion abnormalities at 
      baseline. Logistic regression analysis showed that the LGE area, EDWT and resting 
      wall motion grade predicted wall motion improvement. Comparison of 
      Receiver-Operator-Characteristic (ROC) curves demonstrated that the LGE area was 
      the most important predictor (p < 0.001). Adding information from LGE to the EDWT 
      can decrease the number of false predictions by EDWT alone from 483 to 127 
      segments. CONCLUSION: LGE and EDWT are independent predictors for functional 
      recovery after revascularization. However, LGE appears to be a more important 
      factor and independent of EDWT.
FAU - Krittayaphong, Rungroj
AU  - Krittayaphong R
AD  - Department of Medicine, Division of Cardiology, Faculty of Medicine, Siriraj 
      Hospital, Mahidol University, Bangkok, Thailand. sirkt@mahidol.ac.th
FAU - Laksanabunsong, Pansak
AU  - Laksanabunsong P
FAU - Maneesai, Adisak
AU  - Maneesai A
FAU - Saiviroonporn, Pairash
AU  - Saiviroonporn P
FAU - Udompunturak, Suthipol
AU  - Udompunturak S
FAU - Chaithiraphan, Vithaya
AU  - Chaithiraphan V
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20080922
PL  - England
TA  - J Cardiovasc Magn Reson
JT  - Journal of cardiovascular magnetic resonance : official journal of the Society 
      for Cardiovascular Magnetic Resonance
JID - 9815616
RN  - 0 (Contrast Media)
RN  - K2I13DR72L (Gadolinium DTPA)
SB  - IM
MH  - Adult
MH  - Aged
MH  - *Contrast Media
MH  - *Coronary Artery Bypass
MH  - Coronary Artery Disease/pathology/physiopathology/*surgery
MH  - Female
MH  - *Gadolinium DTPA
MH  - Heart Ventricles/*pathology/physiopathology
MH  - Humans
MH  - Image Enhancement
MH  - Logistic Models
MH  - *Magnetic Resonance Imaging, Cine
MH  - Male
MH  - Middle Aged
MH  - *Myocardial Contraction
MH  - Predictive Value of Tests
MH  - ROC Curve
MH  - Recovery of Function
MH  - Stroke Volume
MH  - Treatment Outcome
MH  - *Ventricular Function, Left
PMC - PMC2561019
EDAT- 2008/09/24 09:00
MHDA- 2008/10/17 09:00
PMCR- 2008/09/22
CRDT- 2008/09/24 09:00
PHST- 2008/05/03 00:00 [received]
PHST- 2008/09/22 00:00 [accepted]
PHST- 2008/09/24 09:00 [pubmed]
PHST- 2008/10/17 09:00 [medline]
PHST- 2008/09/24 09:00 [entrez]
PHST- 2008/09/22 00:00 [pmc-release]
AID - S1097-6647(23)01258-9 [pii]
AID - 1532-429X-10-41 [pii]
AID - 10.1186/1532-429X-10-41 [doi]
PST - epublish
SO  - J Cardiovasc Magn Reson. 2008 Sep 22;10(1):41. doi: 10.1186/1532-429X-10-41.