PMID- 18814927 OWN - NLM STAT- MEDLINE DCOM- 20090410 LR - 20081105 IS - 1872-8227 (Electronic) IS - 0168-8227 (Linking) VI - 82 IP - 2 DP - 2008 Nov TI - Prevalence of diabetes mellitus and other abnormalities of glucose tolerance in young adults aged 20-40 years in North India (Kashmir Valley). PG - 276-81 LID - 10.1016/j.diabres.2008.08.006 [doi] AB - AIMS: To assess the burden of type 2 diabetes mellitus (T2DM) and other abnormalities of glucose tolerance in young-adult (20-40 years) men and non-pregnant women. METHODS: Prevalence of diagnosed T2DM, undiagnosed T2DM and other abnormalities of glucose tolerance studied in 3032 subjects from Kashmir Valley of India. The study included a questionnaire, anthropological measurements, blood sampling, and a standard OGTT. RESULTS: Eight (0.3%) of surveyed subjects were previously diagnosed to have diabetes. Of 3024 subjects screened, prevalence of diabetes, impaired glucose tolerance (IGT), and impaired fasting glycemia [IFG, World Health Organization, Definition, Diagnosis, and Classification of Diabetes Mellitus and its Complications. Part 1. Diagnosis and Classification of Diabetes Mellitus, World Health Organization, Geneva, 1999], IFG [American Diabetes Association, Diagnosis and classification of diabetes mellitus, Diabetes Care 27 (Suppl. 1) (2004) S5-S10] was 2.5%, 2.0%, 11.9% and 26.7%, respectively. Overall, age-adjusted prevalence of T2DM (known plus unknown), IGT, IFG (WHO) and IFG (ADA) was 2.4% (95% CI: 1.9-3.0), 1.6% (95% CI: 1.3-2.2), 11.1% (95% CI: 10.0-12.3), and 25.2% (95% CI: 23.7-26.8), respectively. The difference in diabetes prevalence was significant by age, habitat, family history of diabetes and BMI. The ratio of known-to-unknown diabetes was 1:10. CONCLUSIONS: This is the first large scale study from North India on prevalence of type 2 diabetes in the younger age group of 20-40 years. Abnormal glucose tolerance including undiagnosed T2DM is common in young adults. FAU - Zargar, Abdul Hamid AU - Zargar AH AD - Department of Endocrinology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Kashmir, India. zargarah123@gmail.com FAU - Wani, Abdul Ahad AU - Wani AA FAU - Laway, Bashir Ahmad AU - Laway BA FAU - Masoodi, Shariq Rashid AU - Masoodi SR FAU - Wani, Arshad Iqbal AU - Wani AI FAU - Bashir, Mir Iftikhar AU - Bashir MI FAU - Dar, Farooq Ahmad AU - Dar FA LA - eng PT - Journal Article DEP - 20080923 PL - Ireland TA - Diabetes Res Clin Pract JT - Diabetes research and clinical practice JID - 8508335 SB - IM MH - Adult MH - Diabetes Mellitus/*epidemiology MH - Diabetes Mellitus, Type 2/epidemiology MH - Female MH - Glucose Intolerance/*epidemiology MH - Glucose Tolerance Test MH - Humans MH - India/epidemiology MH - Male MH - Pregnancy MH - Prevalence EDAT- 2008/09/26 09:00 MHDA- 2009/04/11 09:00 CRDT- 2008/09/26 09:00 PHST- 2008/01/18 00:00 [received] PHST- 2008/08/04 00:00 [revised] PHST- 2008/08/12 00:00 [accepted] PHST- 2008/09/26 09:00 [pubmed] PHST- 2009/04/11 09:00 [medline] PHST- 2008/09/26 09:00 [entrez] AID - S0168-8227(08)00383-5 [pii] AID - 10.1016/j.diabres.2008.08.006 [doi] PST - ppublish SO - Diabetes Res Clin Pract. 2008 Nov;82(2):276-81. doi: 10.1016/j.diabres.2008.08.006. Epub 2008 Sep 23.