PMID- 18818067
OWN - NLM
STAT- MEDLINE
DCOM- 20090212
LR  - 20151119
IS  - 1873-4235 (Electronic)
IS  - 0956-5663 (Linking)
VI  - 24
IP  - 4
DP  - 2008 Dec 1
TI  - A sensitive NADH and glucose biosensor tuned by visible light based on thionine 
      bridged carbon nanotubes and gold nanoparticles multilayer.
PG  - 957-63
LID - 10.1016/j.bios.2008.07.066 [doi]
AB  - A NADH and glucose biosensor based on thionine cross-linked multiwalled carbon 
      nanotubes (MWNTs) and Au nanoparticles (Au NPs) multilayer functionalized 
      indium-doped tin oxide (ITO) electrode were presented in this paper. The effect 
      of light irradiation on the enhancement of bioelectrocatalytic processes of the 
      biocatalytic systems by the photovoltaic effect was investigated. This 
      bioelectrode exhibited excellent catalytic activity of the oxidation towards 
      dihydronicotinamide adenine dinucleotide (NADH). Most interesting, the 
      performance of this NADH sensor could be tuned by the visible light. When the 
      biosensor was performed in the dark, the anodic current increased linearly with 
      NADH concentration over the range from 0.5 to 237 microM with detection limit 0.1 
      microM and sensitivity 17 nA microM(-1). The sensitivity became 115 nA microM(-1) 
      with detection limit 0.05 microM with the light irradiation. Compared with the 
      reaction in dark, the sensitivity increased around 7 folds while the detection 
      limit decreased 2 folds. The glucose biosensor also exhibited the same behavior. 
      The linear range was from 10 microM to 2.56 mM with the sensitivity of 7.8 
      microAmM(-1) and detection limit 5.0 microM in the dark. After the light 
      irradiation, the linear range was from 1 microM to 3.25 mM with the sensitivity 
      of 18.5 microA mM(-1) and detection limit 0.7 microM. It indicated a potential to 
      provide an operational access to develop new kinds of photocontrolled 
      dehydrogenase enzyme-based bioelectronics.
FAU - Deng, Liu
AU  - Deng L
AD  - State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of 
      Applied Chemistry, Chinese Academy of Sciences, Changchun, Number 5625, Renmin 
      Road, Jilin 130022, PR China.
FAU - Wang, Yizhe
AU  - Wang Y
FAU - Shang, Li
AU  - Shang L
FAU - Wen, Dan
AU  - Wen D
FAU - Wang, Fuan
AU  - Wang F
FAU - Dong, Shaojun
AU  - Dong S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20080808
PL  - England
TA  - Biosens Bioelectron
JT  - Biosensors & bioelectronics
JID - 9001289
RN  - 0 (Nanotubes, Carbon)
RN  - 0 (Phenothiazines)
RN  - 0U46U6E8UK (NAD)
RN  - 7440-57-5 (Gold)
RN  - EC 1.1.1.47 (Glucose 1-Dehydrogenase)
RN  - IY9XDZ35W2 (Glucose)
RN  - VTT2SAT5H0 (thionine)
SB  - IM
MH  - Biosensing Techniques/*instrumentation/methods
MH  - Electrochemistry/instrumentation/methods
MH  - Electronics/instrumentation
MH  - Equipment Design
MH  - Equipment Failure Analysis
MH  - Glucose/*analysis
MH  - Glucose 1-Dehydrogenase/*chemistry
MH  - Gold/chemistry
MH  - NAD/*analysis
MH  - Nanotubes, Carbon/*chemistry/ultrastructure
MH  - Phenothiazines/*chemistry
MH  - Photometry/*instrumentation/methods
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
EDAT- 2008/09/27 09:00
MHDA- 2009/02/13 09:00
CRDT- 2008/09/27 09:00
PHST- 2008/04/24 00:00 [received]
PHST- 2008/07/07 00:00 [revised]
PHST- 2008/07/25 00:00 [accepted]
PHST- 2008/09/27 09:00 [pubmed]
PHST- 2009/02/13 09:00 [medline]
PHST- 2008/09/27 09:00 [entrez]
AID - S0956-5663(08)00417-X [pii]
AID - 10.1016/j.bios.2008.07.066 [doi]
PST - ppublish
SO  - Biosens Bioelectron. 2008 Dec 1;24(4):957-63. doi: 10.1016/j.bios.2008.07.066. 
      Epub 2008 Aug 8.