PMID- 18823925
OWN - NLM
STAT- MEDLINE
DCOM- 20081224
LR  - 20171116
IS  - 1096-0341 (Electronic)
IS  - 0042-6822 (Linking)
VI  - 381
IP  - 2
DP  - 2008 Nov 25
TI  - Role of class I human leukocyte antigen molecules in early steps of echovirus 
      infection of rhabdomyosarcoma cells.
PG  - 203-14
LID - 10.1016/j.virol.2008.08.006 [doi]
AB  - Several echoviruses use decay accelerating factor (DAF) as a cell surface 
      receptor. However, most of them require additional cell surface coreceptors. We 
      investigated the respective roles of DAF and class I human leukocyte antigen 
      (HLA) molecules in the early steps of the echovirus 11 (EV11) lifecycle in 
      rhabdomyosarcoma (RD) cells. EV11 infection was inhibited at an early stage by 
      anti-beta2-microglobulin (beta2m) and anti-HLA monoclonal antibodies and by a 
      soluble monochain HLA class I molecule. Expression of class I HLA molecules 
      restored the early steps of the EV11 lifecycle, but its expression was not 
      sufficient for EV11 replication and particle production. Expression of HLA class 
      I molecules was associated with leukocyte cell line permissiveness to EV11 
      infection. In conclusion, HLA class I molecules are involved in the early steps 
      of EV11 infection of RD cells and appear to participate in a complex interplay of 
      surface molecules acting as coreceptors, including DAF.
FAU - Chevaliez, Stephane
AU  - Chevaliez S
AD  - Unite de Biologie des Virus Enteriques, Institut Pasteur, Paris, France. 
      stephane.chevaliez@hmn.aphp.fr
FAU - Balanant, Jean
AU  - Balanant J
FAU - Maillard, Patrick
AU  - Maillard P
FAU - Lone, Yu-Chun
AU  - Lone YC
FAU - Lemonnier, Francois A
AU  - Lemonnier FA
FAU - Delpeyroux, Francis
AU  - Delpeyroux F
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20080927
PL  - United States
TA  - Virology
JT  - Virology
JID - 0110674
RN  - 0 (Antibodies, Monoclonal)
RN  - 0 (CD55 Antigens)
RN  - 0 (Histocompatibility Antigens Class I)
RN  - 0 (beta 2-Microglobulin)
SB  - IM
MH  - Animals
MH  - Antibodies, Monoclonal/pharmacology
MH  - CD55 Antigens/metabolism
MH  - CHO Cells
MH  - Cell Line, Tumor
MH  - Cricetinae
MH  - Cricetulus
MH  - Echovirus Infections/*metabolism
MH  - Enterovirus B, Human/*metabolism/physiology
MH  - Gene Expression Regulation
MH  - Histocompatibility Antigens Class I/genetics/*metabolism
MH  - Humans
MH  - Leukocytes/metabolism/virology
MH  - Protein Binding/drug effects
MH  - Rhabdomyosarcoma/*metabolism
MH  - Virus Replication
MH  - beta 2-Microglobulin/metabolism
EDAT- 2008/10/01 09:00
MHDA- 2008/12/25 09:00
CRDT- 2008/10/01 09:00
PHST- 2008/05/07 00:00 [received]
PHST- 2008/06/23 00:00 [revised]
PHST- 2008/08/04 00:00 [accepted]
PHST- 2008/10/01 09:00 [pubmed]
PHST- 2008/12/25 09:00 [medline]
PHST- 2008/10/01 09:00 [entrez]
AID - S0042-6822(08)00518-7 [pii]
AID - 10.1016/j.virol.2008.08.006 [doi]
PST - ppublish
SO  - Virology. 2008 Nov 25;381(2):203-14. doi: 10.1016/j.virol.2008.08.006. Epub 2008 
      Sep 27.