PMID- 18828860 OWN - NLM STAT- MEDLINE DCOM- 20090312 LR - 20210108 IS - 1365-2052 (Electronic) IS - 0268-9146 (Linking) VI - 40 IP - 1 DP - 2009 Feb TI - Polymorphisms in eggshell organic matrix genes are associated with eggshell quality measurements in pedigree Rhode Island Red hens. PG - 110-4 LID - 10.1111/j.1365-2052.2008.01794.x [doi] AB - Novel and traditional eggshell quality measurements were made from up to 2000 commercial pedigree hens for a candidate gene association analysis with organic eggshell matrix genes: ovocleidin-116, osteopontin (SPP1), ovocalyxin-32 (RARRES1), ovotransferrin (LTF), ovalbumin and ovocalyxin-36, as well as key genes in the maintenance and function of the shell gland [estrogen receptor (ESR1) and carbonic anhydrase II (CAII)]. Associations were found for (i) ovalbumin with breaking strength and shell thickness; (ii) ovocleidin-116 with elastic modulus, shell thickness and egg shape; (iii) RARRES1 with mammillary layer thickness; (iv) ESR1 with dynamic stiffness; (v) SPP1 with fracture toughness and (vi) CAII with egg shape. The marker effects are as large as 17% of trait standard deviations and could be used to improve eggshell quality. FAU - Dunn, I C AU - Dunn IC AD - The Roslin Institute and R(D)SVS, University of Edinburgh, Roslin, Midlothian EH25 9PS, UK. ian.dunn@bbsrc.ac.uk FAU - Joseph, N T AU - Joseph NT FAU - Bain, M AU - Bain M FAU - Edmond, A AU - Edmond A FAU - Wilson, P W AU - Wilson PW FAU - Milona, P AU - Milona P FAU - Nys, Y AU - Nys Y FAU - Gautron, J AU - Gautron J FAU - Schmutz, M AU - Schmutz M FAU - Preisinger, R AU - Preisinger R FAU - Waddington, D AU - Waddington D LA - eng GR - BBS/E/D/05191130/BB_/Biotechnology and Biological Sciences Research Council/United Kingdom GR - BBS/E/D/05191132/BB_/Biotechnology and Biological Sciences Research Council/United Kingdom PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20080926 PL - England TA - Anim Genet JT - Animal genetics JID - 8605704 RN - 0 (Egg Proteins) SB - IM MH - Animals MH - Chickens/*genetics MH - Egg Proteins/*genetics MH - Egg Shell/*chemistry MH - *Eggs MH - Female MH - *Polymorphism, Single Nucleotide EDAT- 2008/10/03 09:00 MHDA- 2009/03/13 09:00 CRDT- 2008/10/03 09:00 PHST- 2008/10/03 09:00 [pubmed] PHST- 2009/03/13 09:00 [medline] PHST- 2008/10/03 09:00 [entrez] AID - AGE1794 [pii] AID - 10.1111/j.1365-2052.2008.01794.x [doi] PST - ppublish SO - Anim Genet. 2009 Feb;40(1):110-4. doi: 10.1111/j.1365-2052.2008.01794.x. Epub 2008 Sep 26.