PMID- 18831904 OWN - NLM STAT- MEDLINE DCOM- 20081027 LR - 20191210 IS - 0300-0605 (Print) IS - 0300-0605 (Linking) VI - 36 IP - 5 DP - 2008 Sep-Oct TI - The Angio-Seal arterial closure device for early ambulation after elective percutaneous coronary intervention in patients receiving low-dose enoxaparin. PG - 1077-84 AB - This study evaluated the efficacy and safety of use of the Angio-Seal vascular closure device deployment for early ambulation (2 h) after elective percutaneous coronary intervention in 143 consecutive patients receiving either intravenous low-dose enoxaparin (0.5 mg/kg) or unfractionated heparin (UFH). The initial success rate of Angio-Seal(trade mark) deployment was 98.6%, with no significant difference between the UFH group (98.9%) and the enoxaparin group (98.0%). In-hospital and clinic outcomes were evaluated in the 141 patients with successful Angio-Seal deployment. During hospitalization, there were no deaths, myocardial infarction, urgent target vessel revascularization or bleeding events in either group; three patients in the UFH group and none in the enoxaparin group had minor vascular complications (differences not significant). In clinic follow-up, two patients in the UFH group and none in the enoxaparin group had major vascular complications (differences not significant). Routine use of the Angio-Seal(trade mark) for early ambulation in patients receiving intravenous low-dose enoxaparin compared with UFH provides promising efficacy and safety for daily practice. FAU - Lai, Y-C AU - Lai YC AD - Division of Cardiology, Department of Internal Medicine, Min-Sheng General Hospital, Taoyuan, Taiwan. FAU - Kao, H-L AU - Kao HL FAU - Lin, Y-H AU - Lin YH FAU - Lin, M-S AU - Lin MS FAU - Ho, Y-L AU - Ho YL FAU - Chao, C-L AU - Chao CL LA - eng PT - Evaluation Study PT - Journal Article PL - England TA - J Int Med Res JT - The Journal of international medical research JID - 0346411 RN - 0 (Anticoagulants) RN - 0 (Enoxaparin) RN - 9005-49-6 (Heparin) SB - IM MH - Aged MH - *Angioplasty, Balloon, Coronary/adverse effects/instrumentation MH - Anticoagulants/*therapeutic use MH - *Early Ambulation MH - Enoxaparin/*therapeutic use MH - Femoral Artery/surgery MH - *Hemostatic Techniques/instrumentation MH - Heparin/analogs & derivatives/therapeutic use MH - Humans MH - Male MH - Middle Aged MH - Treatment Outcome EDAT- 2008/10/04 09:00 MHDA- 2008/10/28 09:00 CRDT- 2008/10/04 09:00 PHST- 2008/10/04 09:00 [pubmed] PHST- 2008/10/28 09:00 [medline] PHST- 2008/10/04 09:00 [entrez] AID - 10.1177/147323000803600527 [doi] PST - ppublish SO - J Int Med Res. 2008 Sep-Oct;36(5):1077-84. doi: 10.1177/147323000803600527.