PMID- 18844330
OWN - NLM
STAT- MEDLINE
DCOM- 20090112
LR  - 20081103
IS  - 0952-3499 (Print)
IS  - 0952-3499 (Linking)
VI  - 21
IP  - 6
DP  - 2008 Nov-Dec
TI  - Self-assembled monolayer for low density lipoprotein detection.
PG  - 419-24
LID - 10.1002/jmr.922 [doi]
AB  - Heparin (HEP) has been covalently immobilized onto 4-aminothiophenol (ATP) 
      self-assembled monolayer (SAM) deposited onto gold (Au)-coated glass plate for 
      low density lipoprotein (LDL) detection. The HEP/ATP/Au and LDL/HEP/ATP/Au 
      electrodes have been characterized using cyclic voltammetry (CV) and scanning 
      electron microscopy (SEM). Surface plasmon resonance (SPR) measurements reveal 
      that HEP/ATP/Au electrode is sensitive to detection of the LDL in the range 0.03 
      microM (10 mg/dl)-0.39 microM (130 mg/dl). The values of association and 
      dissociation rate constants in the association phase calculated by kinetic 
      analysis have been found to be k(a) = 9.67 x 10(1) M(-1) s(-1) and k(d) = 2.64 x 
      10(-4) s(-1).
CI  - Copyright 2008 John Wiley & Sons, Ltd.
FAU - Matharu, Zimple
AU  - Matharu Z
AD  - Biomolecular Electronics & Conducting Polymer Research Group, National Physical 
      Laboratory, New Delhi-110012, India.
FAU - Arya, Sunil K
AU  - Arya SK
FAU - Sumana, G
AU  - Sumana G
FAU - Gupta, Vinay
AU  - Gupta V
FAU - Malhotra, B D
AU  - Malhotra BD
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - J Mol Recognit
JT  - Journal of molecular recognition : JMR
JID - 9004580
RN  - 0 (Lipoproteins, LDL)
RN  - 7440-57-5 (Gold)
RN  - 9005-49-6 (Heparin)
SB  - IM
MH  - Electrochemistry
MH  - Electrodes
MH  - Gold/chemistry
MH  - Heparin/chemistry
MH  - Lipoproteins, LDL/*analysis/*chemistry
MH  - Microscopy, Electron, Scanning
MH  - Surface Plasmon Resonance
EDAT- 2008/10/11 09:00
MHDA- 2009/01/13 09:00
CRDT- 2008/10/11 09:00
PHST- 2008/10/11 09:00 [pubmed]
PHST- 2009/01/13 09:00 [medline]
PHST- 2008/10/11 09:00 [entrez]
AID - 10.1002/jmr.922 [doi]
PST - ppublish
SO  - J Mol Recognit. 2008 Nov-Dec;21(6):419-24. doi: 10.1002/jmr.922.