PMID- 18845114
OWN - NLM
STAT- MEDLINE
DCOM- 20090106
LR  - 20181201
IS  - 2162-5220 (Electronic)
IS  - 1710-3568 (Linking)
VI  - 19
IP  - 5
DP  - 2008 Sep-Oct
TI  - Protein contact dermatitis: allergens, pathogenesis, and management.
PG  - 241-51
AB  - Protein contact dermatitis is an allergic skin reaction induced principally by 
      proteins of either animal or plant origin. The clinical presentation is that of a 
      chronic dermatitis, and it is often difficult to differentiate between allergic 
      contact dermatitis and other eczematous dermatoses. One distinguishing clinical 
      feature is that acute flares of pruritus, urticaria, edema, or vesiculation are 
      noted minutes after contact with the causative substances. Additionally, the 
      patch-test result is typically negative, and the scratch- or prick-test result is 
      positive. The pathogenesis of protein contact dermatitis is unclear but may 
      involve a type I (immunoglobulin E [IgE], immediate) hypersensitivity reaction, 
      type IV (cell-mediated delayed) hypersensitivity reaction, and/or a delayed 
      reaction due to IgE-bearing Langerhans' cells. Management involves avoidance of 
      the allergen.
FAU - Levin, Cheryl
AU  - Levin C
AD  - University of Minnesota-Dermatology, Mayo Mail Code 98, 420 Delaware St. SE, 
      Minneapolis, MN 55455-0392, USA. cllevin@gmail.com
FAU - Warshaw, Erin
AU  - Warshaw E
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Dermatitis
JT  - Dermatitis : contact, atopic, occupational, drug
JID - 101207335
RN  - 0 (Allergens)
RN  - 0 (Plant Proteins, Dietary)
RN  - 0 (Proteins)
SB  - IM
MH  - *Allergens
MH  - Animals
MH  - Dermatitis, Allergic Contact/*diagnosis/etiology/therapy
MH  - Dermatitis, Occupational/diagnosis/etiology
MH  - Diagnosis, Differential
MH  - Humans
MH  - Plant Proteins, Dietary/adverse effects
MH  - Proteins/*adverse effects
MH  - Radioallergosorbent Test
MH  - Skin Tests
RF  - 74
EDAT- 2008/10/11 09:00
MHDA- 2009/01/07 09:00
CRDT- 2008/10/11 09:00
PHST- 2008/10/11 09:00 [pubmed]
PHST- 2009/01/07 09:00 [medline]
PHST- 2008/10/11 09:00 [entrez]
PST - ppublish
SO  - Dermatitis. 2008 Sep-Oct;19(5):241-51.