PMID- 18850541 OWN - NLM STAT- MEDLINE DCOM- 20081023 LR - 20190917 IS - 1120-6721 (Print) IS - 1120-6721 (Linking) VI - 18 IP - 5 DP - 2008 Sep-Oct TI - Serum allergen specific immunoglobulin E levels in patients with allergic conjunctivitis. PG - 675-9 AB - PURPOSE: To evaluate serum allergen specific immunoglobulin E (IgE) levels in patients with various types of allergic conjunctivitis. METHODS: Twenty-five patients with seasonal allergic conjunctivitis (SAC), 17 patients with perennial allergic conjunctivitis (PAC), and 10 patients with vernal conjunctivitis (VC) were included in the study. Specific IgE levels to Dermatophagoides pteronyssinus (Dp), Dermatophagoides farinae (Df), mixed grass pollens, and animal epithelia were measured using Pharmacia CAP system (Pharmacia Diagnostic AB, Uppsala, Sweden). RESULTS: The percentage of subjects with specific IgE against Dp and Df was statistically higher in VC (30%) compared to PAC (5.9%) and SAC (0%) (p=0.03). Specific IgE against mixed grass pollens was found in 30% of VC and 40% of SAC, whereas 10% of VC and 8% of SAC patients were found to be hypersensitive to animal epithelia. CONCLUSIONS: Allergic reaction against house dust mites and pollens was common in VC, whereas specific IgE against grass pollens was remarkable in SAC. IgE levels specific to various antigens might be measured by UNICAP system, which is a rapid and practical technology. FAU - Kocabeyoglu, S AU - Kocabeyoglu S AD - Department of Ophthalmology, Hacettepe University School of Medicine, Ankara - Turkey. FAU - Bozkurt, B AU - Bozkurt B FAU - Bilen, O AU - Bilen O FAU - Irkec, M AU - Irkec M FAU - Orhan, M AU - Orhan M LA - eng PT - Journal Article PL - United States TA - Eur J Ophthalmol JT - European journal of ophthalmology JID - 9110772 RN - 0 (Allergens) RN - 0 (Antigens, Dermatophagoides) RN - 0 (Antigens, Plant) RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Adolescent MH - Adult MH - Allergens/*immunology MH - Antigens, Dermatophagoides/*immunology MH - Antigens, Plant/*immunology MH - Conjunctivitis, Allergic/*immunology MH - Epithelial Cells/*immunology MH - Female MH - Humans MH - Immunoenzyme Techniques MH - Immunoglobulin E/*blood MH - Male MH - Poaceae/immunology MH - Pollen/immunology MH - Sensitivity and Specificity EDAT- 2008/10/14 09:00 MHDA- 2008/10/24 09:00 CRDT- 2008/10/14 09:00 PHST- 2008/10/14 09:00 [pubmed] PHST- 2008/10/24 09:00 [medline] PHST- 2008/10/14 09:00 [entrez] AID - 10.1177/112067210801800502 [doi] PST - ppublish SO - Eur J Ophthalmol. 2008 Sep-Oct;18(5):675-9. doi: 10.1177/112067210801800502.