PMID- 18851931
OWN - NLM
STAT- MEDLINE
DCOM- 20090223
LR  - 20151119
IS  - 1878-7568 (Electronic)
IS  - 1742-7061 (Linking)
VI  - 5
IP  - 2
DP  - 2009 Feb
TI  - Sol-gel synthesis and characterization of macroporous calcium phosphate 
      bioceramics containing microporosity.
PG  - 735-42
LID - 10.1016/j.actbio.2008.09.005 [doi]
AB  - Amorphous calcium phosphate powders were precipitated from calcium metal and 
      phosphoric acid in ethanol. Depending on the quantity of reagent, the CaP powders 
      had different chemical compositions and, after heating, formed beta-tricalcium 
      phosphate (beta-TCP), hydroxyapatite (HA) or BCP mixtures. Dilatometric 
      measurements indicated that shrinkage of compacted CaP powders occurred first at 
      around 650 degrees C and continued up to 1200 degrees C. The amorphous CaP 
      powders were mixed with urea beads, compacted under isostatic pressure at 140 MPa 
      and sintered at 1100 degrees C for 5 h. Scanning electron microscopy indicated 
      that macro-microporous ceramics were produced. The ceramics had spherical 
      macropores of 700-1200 microm in diameter, with limited interconnections and a 
      macroporosity of 42% as determined by microcomputed tomography. The micropores 
      ranged from 0.1 to 1 microm in diameter. These ceramics made of HA, beta-TCP or 
      BCP exhibiting both macroporosity and microporosity can be used as bone fillers.
FAU - Fellah, Borhane H
AU  - Fellah BH
AD  - INSERM, U791, Laboratory for Osteoarticular and Dental Tissue Engineering, 
      Faculty of Dental Surgery, University of Nantes, 44042 Nantes, France.
FAU - Layrolle, Pierre
AU  - Layrolle P
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20080925
PL  - England
TA  - Acta Biomater
JT  - Acta biomaterialia
JID - 101233144
RN  - 0 (Calcium Phosphates)
RN  - 0 (Gels)
RN  - 0 (Powders)
RN  - 97Z1WI3NDX (calcium phosphate)
SB  - IM
MH  - Calcium Phosphates/*chemistry
MH  - *Ceramics
MH  - *Gels
MH  - Microscopy, Electron, Scanning
MH  - Powders
MH  - Tomography, X-Ray Computed
EDAT- 2008/10/15 09:00
MHDA- 2009/02/24 09:00
CRDT- 2008/10/15 09:00
PHST- 2008/01/23 00:00 [received]
PHST- 2008/09/05 00:00 [revised]
PHST- 2008/09/05 00:00 [accepted]
PHST- 2008/10/15 09:00 [pubmed]
PHST- 2009/02/24 09:00 [medline]
PHST- 2008/10/15 09:00 [entrez]
AID - S1742-7061(08)00266-3 [pii]
AID - 10.1016/j.actbio.2008.09.005 [doi]
PST - ppublish
SO  - Acta Biomater. 2009 Feb;5(2):735-42. doi: 10.1016/j.actbio.2008.09.005. Epub 2008 
      Sep 25.