PMID- 18853879
OWN - NLM
STAT- MEDLINE
DCOM- 20090108
LR  - 20081015
IS  - 0300-0729 (Print)
IS  - 0300-0729 (Linking)
VI  - 46
IP  - 3
DP  - 2008 Sep
TI  - A frontal mucocele caused by an immune reconstitution inflammatory syndrome in a 
      patient with HIV infection.
PG  - 243-5
AB  - We describe a 55-year-old bisexual Belgian man with a multi-drug resistant HIV 
      infection who developed an Immune Reconstitution Inflammatory Syndrome (IRIS) 
      presenting as a mucocele of the frontal sinus, one year after starting a new 
      effective darunavir containing antiretroviral treatment regimen. His CD4+ 
      lymphocyte count had increased from 3 cells/mm3 prior to the start of the latter 
      treatment to 196 cells/mm3 just before he developed the IRIS phenomenon. IRIS is 
      a paradoxical clinical deterioration during highly active antiretroviral 
      treatment (HAART), due to an exaggerated immune-inflammatory reaction. With the 
      increasing numbers of persons living with HIV infection and the increased use of 
      HAART it is expected that in the future more otolaryngological manifestations of 
      IRIS will be detected.
FAU - Colebunders, B
AU  - Colebunders B
AD  - University of Antwerp, Antwerp, Belgium. bcoleb@itg.be
FAU - Claes, G
AU  - Claes G
FAU - Vlieghe, E
AU  - Vlieghe E
FAU - Demeester, R
AU  - Demeester R
FAU - Moerman, F
AU  - Moerman F
FAU - Colebunders, R
AU  - Colebunders R
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Netherlands
TA  - Rhinology
JT  - Rhinology
JID - 0347242
SB  - IM
MH  - Antiretroviral Therapy, Highly Active/*adverse effects
MH  - CD4 Lymphocyte Count
MH  - HIV Infections/*drug therapy
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/*chemically 
      induced/diagnosis/immunology
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Mucocele/*chemically induced/diagnosis/immunology
MH  - Paranasal Sinus Diseases/*chemically induced/diagnosis/immunology
EDAT- 2008/10/16 09:00
MHDA- 2009/01/09 09:00
CRDT- 2008/10/16 09:00
PHST- 2008/10/16 09:00 [pubmed]
PHST- 2009/01/09 09:00 [medline]
PHST- 2008/10/16 09:00 [entrez]
PST - ppublish
SO  - Rhinology. 2008 Sep;46(3):243-5.