PMID- 1888779
OWN - NLM
STAT- MEDLINE
DCOM- 19911011
LR  - 20190609
IS  - 0006-3002 (Print)
IS  - 0006-3002 (Linking)
VI  - 1084
IP  - 3
DP  - 1991 Jul 30
TI  - Lipoxin formation in fish leucocytes.
PG  - 303-6
AB  - Adherent leucocytes, consisting of mainly macrophages, isolated from the 
      haemopoietic head kidney of five species of fish were challenged with calcium 
      ionophore and the resulting lipoxygenase products were separated and identified 
      by reverse-phase high performance liquid chromatography. Of the fish examined, 
      only adherent leucocytes from the Atlantic salmon and mirror carp generated 
      lipoxins. Atlantic salmon leucocytes synthesized mainly lipoxin (LX) A4/LXA5 and 
      11-trans-LXA4/11-trans-LXA5, while mirror carp produced both LXA4 and LXB4 and 
      their isomers but no 5-series lipoxins. This variation in lipoxin generation 
      suggests that there are differences in the mode(s) of biosynthesis of these 
      compounds between the two species of fish.
FAU - Rowley, A F
AU  - Rowley AF
AD  - Biomedical and Physiological Research Group, School of Biological Sciences, 
      University College of Swansea, U.K.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Biochim Biophys Acta
JT  - Biochimica et biophysica acta
JID - 0217513
RN  - 0 (Hydroxyeicosatetraenoic Acids)
SB  - IM
MH  - Animals
MH  - Carps
MH  - Catfishes
MH  - Cell Adhesion
MH  - Hydroxyeicosatetraenoic Acids/*biosynthesis/isolation & purification
MH  - Kidney/chemistry/enzymology
MH  - Leukocytes/*metabolism
MH  - Macrophages/metabolism
MH  - Salmon
EDAT- 1991/07/30 00:00
MHDA- 1991/07/30 00:01
CRDT- 1991/07/30 00:00
PHST- 1991/07/30 00:00 [pubmed]
PHST- 1991/07/30 00:01 [medline]
PHST- 1991/07/30 00:00 [entrez]
AID - 0005-2760(91)90073-Q [pii]
AID - 10.1016/0005-2760(91)90073-q [doi]
PST - ppublish
SO  - Biochim Biophys Acta. 1991 Jul 30;1084(3):303-6. doi: 
      10.1016/0005-2760(91)90073-q.