PMID- 1890019
OWN - NLM
STAT- MEDLINE
DCOM- 19911011
LR  - 20190903
IS  - 0198-8859 (Print)
IS  - 0198-8859 (Linking)
VI  - 31
IP  - 3
DP  - 1991 Jul
TI  - A physical linkage map of HLA-A, -G, -7.5p, and -F.
PG  - 180-5
AB  - The class I region of the human leukocyte antigen (HLA) complex includes genes 
      encoding the classical transplantation antigens (HLA-A, -B, -C), at least three 
      nonclassical class I genes (HLA-E, -F, and -G), and many class I pseudogenes 
      (including HLA-7.5p). We have used probes from DNA within or flanking the HLA -A, 
      -F, -G, and -7.5p genes to construct a physical linkage map that places the 
      HLA-F, -G, and -7.5p loci in order with respect to HLA-A. The map was constructed 
      using clamped homogeneous electric field pulsed-field gel electrophoresis. DNA 
      was isolated from LCL 721 (A1:B8, A2:B5), a human Epstein-Barr virus-transformed 
      lymphoblastoid cell line (LCL), and from two gamma-irradiation-induced mutants of 
      LCL 721 lacking complementary class I haplotypes. The physical linkage data place 
      HLA-G closest to HLA-A and place HLA-7.5p between HLA-G and HLA-F. The map 
      constructed supports a maximum distance of 490 kilobases between HLA-A and HLA-F.
FAU - Schmidt, C M
AU  - Schmidt CM
AD  - Department of Laboratory Medicine, University of Minnesota, Minneapolis 55455.
FAU - Orr, H T
AU  - Orr HT
LA  - eng
GR  - AI 18124/AI/NIAID NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Hum Immunol
JT  - Human immunology
JID - 8010936
RN  - 0 (HLA Antigens)
RN  - 0 (HLA-A Antigens)
RN  - 0 (HLA-F antigens)
RN  - 0 (HLA-G Antigens)
RN  - 0 (Histocompatibility Antigens Class I)
SB  - IM
GS  - HLA-7.5p
GS  - HLA-A
GS  - HLA-B
GS  - HLA-C
GS  - HLA-E
GS  - HLA-F
GS  - HLA-G
MH  - Cell Line, Transformed
MH  - Chromosome Mapping
MH  - *Genes, MHC Class I
MH  - Genetic Linkage
MH  - HLA Antigens/*genetics
MH  - HLA-A Antigens/*genetics
MH  - HLA-G Antigens
MH  - Histocompatibility Antigens Class I/*genetics
MH  - Humans
MH  - *Major Histocompatibility Complex
MH  - Pseudogenes
MH  - Restriction Mapping
EDAT- 1991/07/01 00:00
MHDA- 1991/07/01 00:01
CRDT- 1991/07/01 00:00
PHST- 1991/07/01 00:00 [pubmed]
PHST- 1991/07/01 00:01 [medline]
PHST- 1991/07/01 00:00 [entrez]
AID - 0198-8859(91)90024-4 [pii]
AID - 10.1016/0198-8859(91)90024-4 [doi]
PST - ppublish
SO  - Hum Immunol. 1991 Jul;31(3):180-5. doi: 10.1016/0198-8859(91)90024-4.