PMID- 18945515 OWN - NLM STAT- MEDLINE DCOM- 20090409 LR - 20090814 IS - 1527-3296 (Electronic) IS - 0196-6553 (Linking) VI - 37 IP - 2 DP - 2009 Mar TI - Efficacy of an expanded ventilator bundle for the reduction of ventilator-associated pneumonia in the medical intensive care unit. PG - 172-5 LID - 10.1016/j.ajic.2008.05.010 [doi] AB - The ventilator bundle (VB) includes a group of clinical maneuvers (head-of-bed elevation, "sedation vacation," deep vein thrombosis prophylaxis, and peptic ulcer disease prophylaxis) to improve outcomes in patients undergoing mechanical ventilation. We modified the standard VB in our medical intensive care unit to include a group of respiratory therapist-driven protocols and, postimplementation, observed a statistically significant (P = .0006) reduction in ventilator-associated pneumonia (VAP), from a median of 14.1 cases/10(3) ventilator-days (interquartile range [IQR] = 12.1 to 20.6) to 0 cases/10(3) ventilator-days (IQR = 0 to 1.1). FAU - Blamoun, John AU - Blamoun J AD - Division of Pulmonary Medicine, School of Health and Medical Sciences, Seton Hall University, South Orange, NJ 07079, USA. FAU - Alfakir, Maria AU - Alfakir M FAU - Rella, Marie E AU - Rella ME FAU - Wojcik, Janice M AU - Wojcik JM FAU - Solis, Roberto A AU - Solis RA FAU - Anees Khan, M AU - Anees Khan M FAU - DeBari, Vincent A AU - DeBari VA LA - eng PT - Journal Article DEP - 20081022 PL - United States TA - Am J Infect Control JT - American journal of infection control JID - 8004854 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Female MH - Humans MH - Incidence MH - Intensive Care Units MH - Male MH - Middle Aged MH - Pneumonia, Ventilator-Associated/*epidemiology/*prevention & control MH - Ventilators, Mechanical/*adverse effects MH - Young Adult EDAT- 2008/10/24 09:00 MHDA- 2009/04/10 09:00 CRDT- 2008/10/24 09:00 PHST- 2008/04/01 00:00 [received] PHST- 2008/05/07 00:00 [revised] PHST- 2008/05/08 00:00 [accepted] PHST- 2008/10/24 09:00 [pubmed] PHST- 2009/04/10 09:00 [medline] PHST- 2008/10/24 09:00 [entrez] AID - S0196-6553(08)00690-1 [pii] AID - 10.1016/j.ajic.2008.05.010 [doi] PST - ppublish SO - Am J Infect Control. 2009 Mar;37(2):172-5. doi: 10.1016/j.ajic.2008.05.010. Epub 2008 Oct 22.