PMID- 18952214
OWN - NLM
STAT- MEDLINE
DCOM- 20090511
LR  - 20090316
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1216
IP  - 14
DP  - 2009 Apr 3
TI  - Development of a matrix solid-phase dispersion method for the simultaneous 
      determination of pyrethroid and organochlorinated pesticides in cattle feed.
PG  - 2832-42
LID - 10.1016/j.chroma.2008.10.026 [doi]
AB  - A matrix solid-phase dispersion (MSPD) method was developed for the simultaneous 
      extraction of 36 common pesticides and breakdown products (mostly pyrethroids and 
      organochlorines) in cattle feed. Different parameters affecting the extraction 
      efficiency (such as dispersing phase, clean-up adsorbent and elution volume) were 
      investigated. The experimental procedure was optimized using a multivariate 
      statistical approach and the final analyses were carried out by GC-muECD. Several 
      protocols for extract purification were also studied. As far as we know, this is 
      the first application of MSPD for the extraction of most of the target pesticides 
      from animal feed. Using the optimized extraction conditions, the method was 
      validated in terms of accuracy, and precision (within-a-day and among-days), 
      using a certified reference material (CRM 115) as well as spiked cattle 
      feedingstuffs at different concentration levels. A matrix effect study was also 
      carried out using various real samples. The recoveries were satisfactory (>75% in 
      most cases) and the quantification limits, at the sub-ngg(-1) or low-ngg(-1) 
      level, complied with the regulated maximum residue levels (MRLs) in animal feed 
      and in main crops used in the preparation of cattle feeding materials. Finally, 
      the MSPD-GC-muECD methodology was applied to the analysis of real cattle feed 
      samples collected in farms of dairy cattle from NW Spain.
FAU - Fernandez-Alvarez, Maria
AU  - Fernandez-Alvarez M
AD  - Departamento de Quimica Analitica, Nutricion y Bromatologia, Instituto de 
      Investigacion y Analisis Alimentario, Universidad de Santiago de Compostela, 
      Santiago de Compostela 15782, Spain.
FAU - Llompart, Maria
AU  - Llompart M
FAU - Lamas, J Pablo
AU  - Lamas JP
FAU - Lores, Marta
AU  - Lores M
FAU - Garcia-Jares, Carmen
AU  - Garcia-Jares C
FAU - Cela, Rafael
AU  - Cela R
FAU - Dagnac, Thierry
AU  - Dagnac T
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20081014
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Pesticide Residues)
RN  - 0 (Pyrethrins)
SB  - IM
MH  - Animal Feed/*analysis
MH  - Animals
MH  - Cattle
MH  - Chromatography, Gas/*methods
MH  - Food Contamination/*analysis
MH  - Pesticide Residues/*analysis
MH  - Pyrethrins/*analysis
MH  - Solid Phase Extraction/*methods
EDAT- 2008/10/28 09:00
MHDA- 2009/05/12 09:00
CRDT- 2008/10/28 09:00
PHST- 2008/07/07 00:00 [received]
PHST- 2008/10/01 00:00 [revised]
PHST- 2008/10/08 00:00 [accepted]
PHST- 2008/10/28 09:00 [pubmed]
PHST- 2009/05/12 09:00 [medline]
PHST- 2008/10/28 09:00 [entrez]
AID - S0021-9673(08)01766-4 [pii]
AID - 10.1016/j.chroma.2008.10.026 [doi]
PST - ppublish
SO  - J Chromatogr A. 2009 Apr 3;1216(14):2832-42. doi: 10.1016/j.chroma.2008.10.026. 
      Epub 2008 Oct 14.