PMID- 18955223 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20110714 LR - 20240109 IS - 1741-427X (Print) IS - 1741-4288 (Electronic) IS - 1741-427X (Linking) VI - 6 IP - 1 DP - 2009 Mar TI - Chinese Herbal Medicine for Dysfunctional Uterine Bleeding: a Meta-analysis. PG - 99-105 LID - 10.1093/ecam/nem063 [doi] AB - We conducted a systematic review to evaluate the efficacy and safety of Chinese herbal medicine (CHM) for dysfunctional uterine bleeding (DUB) by performing a meta-analysis. Randomized controlled trials (RCTs) or quasi-RCTs comparing CHM vs no treatment, placebo, conventional western medicine (CWM), or general non-specific surgical treatment for DUB were identified by electronic and manual searches. Trials of CHM treatments with CWM treatments were compared with CWM treatments alone. Jadad scale and allocation concealment were used to assess the quality of included studies. Four RCTs or quasi-RCTs involving 525 patients were included. The methodological quality was poor in all trials except one trial. No serious adverse events were reported in the included studies. With the lack of trials comparing CHM with no treatment or placebo, it is impossible to accurately evaluate the efficacy of CHM. However, CHM in these studies seem to show an encouraging comparative effectiveness with CWM. More RCTs with a higher quality are required. FAU - Tu, Xiang AU - Tu X AD - College of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan Province, China. E- tuxiang2005@163.com. FAU - Huang, Gaomin AU - Huang G FAU - Tan, Shengkui AU - Tan S LA - eng PT - Journal Article DEP - 20070630 PL - United States TA - Evid Based Complement Alternat Med JT - Evidence-based complementary and alternative medicine : eCAM JID - 101215021 PMC - PMC2644269 EDAT- 2008/10/29 09:00 MHDA- 2008/10/29 09:01 PMCR- 2010/03/01 CRDT- 2008/10/29 09:00 PHST- 2008/10/29 09:00 [pubmed] PHST- 2008/10/29 09:01 [medline] PHST- 2008/10/29 09:00 [entrez] PHST- 2010/03/01 00:00 [pmc-release] AID - nem063 [pii] AID - 10.1093/ecam/nem063 [doi] PST - ppublish SO - Evid Based Complement Alternat Med. 2009 Mar;6(1):99-105. doi: 10.1093/ecam/nem063. Epub 2007 Jun 30.