PMID- 18955271
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20200929
IS  - 1741-4288 (Electronic)
IS  - 1741-427X (Print)
IS  - 1741-427X (Linking)
VI  - 7
IP  - 1
DP  - 2010 Mar
TI  - Can homeopathy bring additional benefits to thalassemic patients on hydroxyurea 
      therapy? Encouraging results of a preliminary study.
PG  - 129-36
LID - 10.1093/ecam/nem161 [doi]
AB  - Several homeopathic remedies, namely, Pulsatilla Nigricans (30th potency), 
      Ceanothus Americanus (both mother tincture and 6th potency) and Ferrum Metallicum 
      (30th potency) selected as per similia principles were administered to 38 
      thalassemic patients receiving Hydroxyurea (HU) therapy for a varying period of 
      time. Levels of serum ferritin (SF), fetal hemoglobin (HbF), hemoglobin (Hb), 
      platelet count (PC), mean corpuscular volume (MCV), mean corpuscular hemoglobin 
      concentration (MCHC), mean corpuscular hemoglobin (MCH), white blood cell (WBC) 
      count, bilirubin content, alanine amino transferase (ALT), aspartate amino 
      transferase (AST) and serum total protein content of patients were determined 
      before and 3 months after administration of the homeopathic remedies in 
      combination with HU to evaluate additional benefits, if any, derived by the 
      homeopathic remedies, by comparing the data with those of 38 subjects receiving 
      only HU therapy. Preliminary results indicated that there was a significant 
      decrease in the SF and increase in HbF levels in the combined, treated subjects. 
      Although the changes in other parameters were not so significant, there was a 
      significant decrease in size of spleen in most patients with spleenomegaly and 
      improvement in general health conditions along with an increased gap between 
      transfusions in most patients receiving the combined homeopathic treatment. The 
      homeopathic remedies being inexpensive and without any known side-effects seem to 
      have great potentials in bringing additional benefits to thalassemic patients; 
      particularly in the developing world where blood transfusions suffer from 
      inadequate screening and fall short of the stringent safety standards followed in 
      the developed countries. Further independent studies are encouraged.
FAU - Banerjee, Antara
AU  - Banerjee A
AD  - Cytogenetics and Molecular Biology Laboratory, Department of Zoology, University 
      of Kalyani, Kalyani-741 235, Institute of Genetic Engineering, 30 Thakurhat Road, 
      Badu, Kolkata-700 128, Directorate of Research, Bidhan Chandra Krishi 
      Viswavidyalaya, Kalyani, West Bengal, India and Boiron Laboratory, 20 Rue de la 
      Liberation, Sainte-Foy-Les-Lyon, France.
FAU - Chakrabarty, Sudipa Basu
AU  - Chakrabarty SB
FAU - Karmakar, Susanta Roy
AU  - Karmakar SR
FAU - Chakrabarty, Amit
AU  - Chakrabarty A
FAU - Biswas, Surjyo Jyoti
AU  - Biswas SJ
FAU - Haque, Saiful
AU  - Haque S
FAU - Das, Debarsi
AU  - Das D
FAU - Paul, Saili
AU  - Paul S
FAU - Mandal, Biswapati
AU  - Mandal B
FAU - Naoual, Boujedaini
AU  - Naoual B
FAU - Belon, Philippe
AU  - Belon P
FAU - Khuda-Bukhsh, Anisur Rahman
AU  - Khuda-Bukhsh AR
LA  - eng
PT  - Journal Article
DEP - 20071029
PL  - United States
TA  - Evid Based Complement Alternat Med
JT  - Evidence-based complementary and alternative medicine : eCAM
JID - 101215021
PMC - PMC2816384
OTO - NOTNLM
OT  - Ceanothus Americanus
OT  - Ferrum Metallicum
OT  - Hydroxyurea
OT  - Pulsatilla Nigricans
OT  - Thalassemia
OT  - ferritin
OT  - fetal hemoglobin
OT  - homeopathic remedy
EDAT- 2008/10/29 09:00
MHDA- 2008/10/29 09:01
PMCR- 2007/10/29
CRDT- 2008/10/29 09:00
PHST- 2007/05/09 00:00 [received]
PHST- 2007/09/05 00:00 [accepted]
PHST- 2008/10/29 09:00 [pubmed]
PHST- 2008/10/29 09:01 [medline]
PHST- 2008/10/29 09:00 [entrez]
PHST- 2007/10/29 00:00 [pmc-release]
AID - nem161 [pii]
AID - 10.1093/ecam/nem161 [doi]
PST - ppublish
SO  - Evid Based Complement Alternat Med. 2010 Mar;7(1):129-36. doi: 
      10.1093/ecam/nem161. Epub 2007 Oct 29.