PMID- 18956030
OWN - NLM
STAT- MEDLINE
DCOM- 20090109
LR  - 20081028
IS  - 1359-7345 (Print)
IS  - 1359-7345 (Linking)
IP  - 41
DP  - 2008 Nov 7
TI  - Functional biomimetic models for the active site in the respiratory enzyme 
      cytochrome c oxidase.
PG  - 5065-76
LID - 10.1039/b808070b [doi]
AB  - A functional analog of the active site in the respiratory enzyme, cytochrome c 
      oxidase (CcO) reproduces every feature in CcO's active site: a myoglobin-like 
      heme (heme a3), a distal tridentate imidazole copper complex (Cu(B)), a phenol 
      (Tyr244), and a proximal imidazole. When covalently attached to a 
      liquid-crystalline SAM film on an Au electrode, this functional model 
      continuously catalyzes the selective four-electron reduction of dioxygen at 
      physiological potential and pH, under rate-limiting electron flux (as occurs in 
      CcO).
FAU - Collman, James P
AU  - Collman JP
AD  - Stanford University, Chemistry Department, Stanford, CA-94305-5080, USA. 
      jpc@stanford.edu
FAU - Decreau, Richard A
AU  - Decreau RA
LA  - eng
GR  - 5R01 GM-17880-35/GM/NIGMS NIH HHS/United States
GR  - GM-69658-R01/GM/NIGMS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20080904
PL  - England
TA  - Chem Commun (Camb)
JT  - Chemical communications (Cambridge, England)
JID - 9610838
RN  - EC 1.9.3.1 (Electron Transport Complex IV)
SB  - IM
MH  - *Biomimetics
MH  - Catalysis
MH  - Catalytic Domain
MH  - Electrodes
MH  - Electron Transport
MH  - Electron Transport Complex IV/*chemistry/metabolism
MH  - *Models, Biological
RF  - 25
EDAT- 2008/10/29 09:00
MHDA- 2009/01/10 09:00
CRDT- 2008/10/29 09:00
PHST- 2008/10/29 09:00 [pubmed]
PHST- 2009/01/10 09:00 [medline]
PHST- 2008/10/29 09:00 [entrez]
AID - 10.1039/b808070b [doi]
PST - ppublish
SO  - Chem Commun (Camb). 2008 Nov 7;(41):5065-76. doi: 10.1039/b808070b. Epub 2008 Sep 
      4.