PMID- 18972547
OWN - NLM
STAT- MEDLINE
DCOM- 20090608
LR  - 20191210
IS  - 1531-8257 (Electronic)
IS  - 0885-3185 (Linking)
VI  - 24
IP  - 2
DP  - 2009 Jan 30
TI  - Odor identification test as an indicator of idiopathic REM sleep behavior 
      disorder.
PG  - 268-73
LID - 10.1002/mds.22361 [doi]
AB  - Reduction of olfactory function in idiopathic rapid-eye-movement (REM) sleep 
      behavior disorder (iRBD) is of the same magnitude as that found in patients with 
      Parkinson's disease (PD) and dementia with Lewy bodies (DLB). We assessed 
      olfactory function using the Odor Stick Identification Test for Japanese (OSIT-J) 
      in 48 Japanese patients with iRBD, 21 with PD, and 34 with obstructive sleep 
      apnea syndrome (OSAS). Possible score of the OSIT-J ranges from 0 to 12. OSIT-J 
      scores were 4.9 +/- 2.8 in patients with iRBD, 4.8 +/- 2.8 in patients with PD, 
      and 9.9 +/- 1.4 in OSAS patients. An OSIT-J score of 8.5 was associated with a 
      sensitivity of 88.2 and 85.3%, respectively, and specificity of 83.3 and 85.7%, 
      respectively, in differentiating iRBD or PD patients from OSAS patients. Odor 
      identification is impaired in Japanese patients with iRBD and PD. The results 
      suggest that OSIT-J, which is a short and simple nonlexical olfactory 
      identification test, can be useful as a clinical indicator for iRBD with Lewy 
      body formation and is appropriate in the Japanese elderly population.
FAU - Miyamoto, Tomoyuki
AU  - Miyamoto T
AD  - Department of Neurology, Center of Sleep Medicine, Dokkyo Medical University 
      School of Medicine, Tochigi, Japan. miyatomo@dokkyomed.ac.jp
FAU - Miyamoto, Masayuki
AU  - Miyamoto M
FAU - Iwanami, Masaoki
AU  - Iwanami M
FAU - Suzuki, Keisuke
AU  - Suzuki K
FAU - Inoue, Yuichi
AU  - Inoue Y
FAU - Hirata, Koichi
AU  - Hirata K
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Mov Disord
JT  - Movement disorders : official journal of the Movement Disorder Society
JID - 8610688
SB  - IM
MH  - Aged
MH  - Continuous Positive Airway Pressure
MH  - *Discrimination, Psychological
MH  - Dreams
MH  - Female
MH  - Humans
MH  - Japan
MH  - Lewy Body Disease/complications/diagnosis/physiopathology
MH  - Male
MH  - Middle Aged
MH  - *Odorants
MH  - Olfaction Disorders/*diagnosis/etiology/physiopathology
MH  - Polysomnography
MH  - Predictive Value of Tests
MH  - REM Sleep Behavior Disorder/complications/*diagnosis/physiopathology
MH  - *Recognition, Psychology
MH  - Sensitivity and Specificity
MH  - Sleep Apnea, Obstructive/physiopathology/therapy
EDAT- 2008/10/31 09:00
MHDA- 2009/06/09 09:00
CRDT- 2008/10/31 09:00
PHST- 2008/10/31 09:00 [pubmed]
PHST- 2009/06/09 09:00 [medline]
PHST- 2008/10/31 09:00 [entrez]
AID - 10.1002/mds.22361 [doi]
PST - ppublish
SO  - Mov Disord. 2009 Jan 30;24(2):268-73. doi: 10.1002/mds.22361.