PMID- 18975441
OWN - NLM
STAT- MEDLINE
DCOM- 20081107
LR  - 20131121
IS  - 1053-0894 (Print)
IS  - 1053-0894 (Linking)
VI  - 18
IP  - 10
DP  - 2008 Oct
TI  - Mycobacterium-avium-intracellulare complex immune reconstitution inflammatory 
      syndrome in HIV/AIDS presenting as osteomyelitis.
PG  - 515-8
AB  - We report a case of osteomyelitis due to Mycobacterium avium-intracellulare 
      complex (MAC) in an AIDS patient shortly after the initiation of antiretroviral 
      therapy with subsequent immune reconstitution inflammatory syndrome (IRIS). He 
      improved after surgical debridement and treatment with clarithromycin, 
      ethambutol, rifabutin, and low-dose corticosteroids. Antiretroviral therapy was 
      not interrupted. MAC should be suspected in IRIS-related complications such as 
      osteomyelitis.
FAU - Kahlon, Summerpal S
AU  - Kahlon SS
AD  - Melbourne Internal Medicaine Associates, Melbourne, Florida, USA.
FAU - East, Jeffrey W
AU  - East JW
FAU - Sarria, Juan C
AU  - Sarria JC
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - AIDS Read
JT  - The AIDS reader
JID - 9206753
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Anti-Inflammatory Agents)
RN  - 1W306TDA6S (Rifabutin)
RN  - 8G167061QZ (Ethambutol)
RN  - H1250JIK0A (Clarithromycin)
SB  - IM
MH  - Adult
MH  - Anti-Bacterial Agents/therapeutic use
MH  - Anti-Inflammatory Agents/therapeutic use
MH  - Clarithromycin/therapeutic use
MH  - Ethambutol/therapeutic use
MH  - Female
MH  - HIV Infections/*complications/drug therapy/immunology
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/*diagnosis
MH  - Male
MH  - Middle Aged
MH  - Mycobacterium avium Complex/isolation & purification
MH  - Mycobacterium avium-intracellulare Infection/*diagnosis/drug therapy/etiology
MH  - Osteomyelitis/*diagnosis/drug therapy/etiology
MH  - Rifabutin/therapeutic use
MH  - Viral Load
EDAT- 2008/11/04 09:00
MHDA- 2008/11/08 09:00
CRDT- 2008/11/04 09:00
PHST- 2008/11/04 09:00 [pubmed]
PHST- 2008/11/08 09:00 [medline]
PHST- 2008/11/04 09:00 [entrez]
PST - ppublish
SO  - AIDS Read. 2008 Oct;18(10):515-8.