PMID- 18979812
OWN - NLM
STAT- MEDLINE
DCOM- 20081209
LR  - 20220129
VI  - 11
IP  - Pt 1
DP  - 2008
TI  - A statistical motion model based on biomechanical simulations for data fusion 
      during image-guided prostate interventions.
PG  - 737-44
AB  - A method is described for generating a patient-specific, statistical motion model 
      (SMM) of the prostate gland. Finite element analysis (FEA) is used to simulate 
      the motion of the gland using an ultrasound-based 3D FE model over a range of 
      plausible boundary conditions and soft-tissue properties. By applying principal 
      component analysis to the displacements of the FE mesh node points inside the 
      gland, the simulated deformations are then used as training data to construct the 
      SMM. The SMM is used to both predict the displacement field over the whole gland 
      and constrain a deformable surface registration algorithm, given only a small 
      number of target points on the surface of the deformed gland. Using 3D 
      transrectal ultrasound images of the prostates of five patients, acquired before 
      and after imposing a physical deformation, to evaluate the accuracy of predicted 
      landmark displacements, the mean target registration error was found to be less 
      than 1.9 mm.
FAU - Hu, Yipeng
AU  - Hu Y
AD  - Centre for Medical Image Computing, University College London, London, UK.
FAU - Morgan, Dominic
AU  - Morgan D
FAU - Ahmed, Hashim Uddin
AU  - Ahmed HU
FAU - Pendse, Doug
AU  - Pendse D
FAU - Sahu, Mahua
AU  - Sahu M
FAU - Allen, Clare
AU  - Allen C
FAU - Emberton, Mark
AU  - Emberton M
FAU - Hawkes, David
AU  - Hawkes D
FAU - Barratt, Dean
AU  - Barratt D
LA  - eng
GR  - G0701302/MRC_/Medical Research Council/United Kingdom
GR  - G1002509/MRC_/Medical Research Council/United Kingdom
PT  - Journal Article
PL  - Germany
TA  - Med Image Comput Comput Assist Interv
JT  - Medical image computing and computer-assisted intervention : MICCAI ... 
      International Conference on Medical Image Computing and Computer-Assisted 
      Intervention
JID - 101249582
SB  - IM
MH  - *Artifacts
MH  - *Biophysical Phenomena
MH  - Computer Simulation
MH  - Humans
MH  - Image Enhancement/*methods
MH  - Male
MH  - *Models, Biological
MH  - Models, Statistical
MH  - Motion
MH  - Prostatectomy/methods
MH  - Prostatic Neoplasms/*diagnostic imaging/*surgery
MH  - Surgery, Computer-Assisted/methods
MH  - Ultrasonography, Interventional/*methods
EDAT- 2008/11/05 09:00
MHDA- 2008/12/17 09:00
CRDT- 2008/11/05 09:00
PHST- 2008/11/05 09:00 [pubmed]
PHST- 2008/12/17 09:00 [medline]
PHST- 2008/11/05 09:00 [entrez]
AID - 10.1007/978-3-540-85988-8_88 [doi]
PST - ppublish
SO  - Med Image Comput Comput Assist Interv. 2008;11(Pt 1):737-44. doi: 
      10.1007/978-3-540-85988-8_88.