PMID- 18981632
OWN - NLM
STAT- MEDLINE
DCOM- 20090601
LR  - 20221207
IS  - 1349-7235 (Electronic)
IS  - 0918-2918 (Linking)
VI  - 47
IP  - 21
DP  - 2008
TI  - Smell identification in Japanese Parkinson's disease patients: using the odor 
      stick identification test for Japanese subjects.
PG  - 1887-92
AB  - OBJECTIVE: The purpose of the present study was to clarify the olfactory 
      functions of Japanese patients with idiopathic Parkinson's disease (IPD) using 
      the odor stick identification test for Japanese (OSIT-J). METHODS: Fifty-four 
      non-demented IPD patients (33 men and 21 women), ranging in age from 43 to 81 
      years (69.7+/-8.1 years) and 50 age- and gender-matched healthy controls who 
      reported having no olfactory complaints were enrolled. OSIT-J consisted of 12 
      odorants familiar to Japanese subjects. Each subject sniffed each odor that was 
      applied to paraffin paper. Next the subject chose 1 of 6 answers: 4 pictures 
      associated with the odors labeled with their names, one of which was correct, and 
      2 other ones ("unknown" and "not detected"). RESULTS: The number of correct 
      answers was significantly lower in the IPD group (4.4+/-2.7) than in the normal 
      group (8.3+/-2.2) (p<0.0001). Even in IPD patients who could smell normal 
      strength odors in subjective symptom, the number of correct answers decreased. 
      The number of correct answers was not correlated with motor function, disease 
      duration, or medication. CONCLUSION: The present study demonstrated that the 
      smell identification ability of Japanese IPD patients was impaired based on the 
      OSIT-J.
FAU - Iijima, Mutsumi
AU  - Iijima M
AD  - Department of Neurology, Tokyo Women's Medical University. mutumi@nij.twmu.ac.jp
FAU - Kobayakawa, Tatsu
AU  - Kobayakawa T
FAU - Saito, Sachiko
AU  - Saito S
FAU - Osawa, Mikio
AU  - Osawa M
FAU - Tsutsumi, Yukiko
AU  - Tsutsumi Y
FAU - Hashimoto, Shiori
AU  - Hashimoto S
FAU - Iwata, Makoto
AU  - Iwata M
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20081104
PL  - Japan
TA  - Intern Med
JT  - Internal medicine (Tokyo, Japan)
JID - 9204241
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - *Asian People
MH  - Diagnostic Tests, Routine/instrumentation/methods
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Odorants
MH  - Olfaction Disorders/*complications/*diagnosis/physiopathology
MH  - Olfactory Perception/*physiology
MH  - Parkinson Disease/*complications/diagnosis/physiopathology
EDAT- 2008/11/05 09:00
MHDA- 2009/06/02 09:00
CRDT- 2008/11/05 09:00
PHST- 2008/11/05 09:00 [pubmed]
PHST- 2009/06/02 09:00 [medline]
PHST- 2008/11/05 09:00 [entrez]
AID - JST.JSTAGE/internalmedicine/47.1345 [pii]
AID - 10.2169/internalmedicine.47.1345 [doi]
PST - ppublish
SO  - Intern Med. 2008;47(21):1887-92. doi: 10.2169/internalmedicine.47.1345. Epub 2008 
      Nov 4.