PMID- 18984979
OWN - NLM
STAT- MEDLINE
DCOM- 20090217
LR  - 20121115
IS  - 1016-5169 (Print)
IS  - 1016-5169 (Linking)
VI  - 36
IP  - 5
DP  - 2008 Jul
TI  - [Transcatheter closure of secundum atrial septal defects using the Amplatzer 
      septal occluder in adult patients: our first clinical experiences].
PG  - 287-93
AB  - OBJECTIVES: We evaluated short-term results of transcatheter closure of secundum 
      atrial septal defects (ASD) with the Amplatzer septal occluder (ASO) in adults. 
      STUDY DESIGN: The study included 12 patients (6 males, 6 females; mean age 31+/-9 
      years; range 17 to 54 years) who underwent transcatheter ASD closure with the ASO 
      device. Prior to the procedure, the mean pulmonary to systemic flow ratio was 
      1.9+/-0.3 (range 1.5 to 2.6). The mean ASD diameter measured by transesophageal 
      echocardiography was 13.9+/-2.8 mm, the mean stretched diameter of ASD measured 
      by balloon sizing was 15.8+/-3.4 mm, and the mean ASO device diameter was 
      17.3+/-4.7 mm. The patients were evaluated before and six months after the 
      procedure by echocardiography, electrocardiography, and the New York Heart 
      Association (NYHA) functional classification. RESULTS: Transcatheter ASD closure 
      was successfully performed in 11 patients (91.7%). The mean procedure time was 72 
      minutes. There was no residual shunt at six months after closure. No serious 
      complications occurred during the procedure and within a mean follow-up of 
      11.6+/-2.3 months. Echocardiographic examination at six months showed significant 
      decreases in right ventricular end-diastolic diameter (VEDD) (p=0.007), 
      right/left VEDD ratio (0.003), systolic pulmonary artery pressure (p=0.017), and 
      significant increases in left ventricular ejection fraction (p=0.014) and left 
      VEDD (p=0.005). There were significant decreases in maximum (p=0.003) and minimum 
      (p=0.006) P-wave durations, and P-wave dispersion (p=0.028). The NYHA functional 
      capacity improved significantly from 1.8+/-0.8 to 1.3+/-0.5 (p=0.014). 
      CONCLUSION: Transcatheter closure of secundum ASD with the ASO device is a safe 
      and effective method in adult patients, resulting in significant improvement in 
      clinical symptoms and cardiac dimensions.
FAU - Kaya, Mehmet Gungor
AU  - Kaya MG
AD  - Erciyes Universitese Tip Fakultesi, Kardiyoloji Anabilim Dali, Kayseri, Turkey. 
      drmgkaya@yahoo.com
FAU - Ozdogru, Ibrahim
AU  - Ozdogru I
FAU - Baykan, Ali
AU  - Baykan A
FAU - Dogan, Ali
AU  - Dogan A
FAU - Inanc, Tugrul
AU  - Inanc T
FAU - Dogdu, Orhan
AU  - Dogdu O
FAU - Uzum, Kazim
AU  - Uzum K
FAU - Narin, Nazmi
AU  - Narin N
FAU - Topsakal, Ramazan
AU  - Topsakal R
FAU - Ergin, Ali
AU  - Ergin A
FAU - Oguzhan, Abdurrahman
AU  - Oguzhan A
FAU - Eryol, Namik Kemal
AU  - Eryol NK
LA  - tur
PT  - English Abstract
PT  - Journal Article
TT  - Eriskin hastalarda sekundum atriyal septal defektlerin Amplatzer cihazi ile 
      kapatilmasi: Ilk klinik deneyimlerimiz.
PL  - Turkey
TA  - Turk Kardiyol Dern Ars
JT  - Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir
JID - 9426239
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Cardiac Catheterization/*methods
MH  - Catheterization/*methods
MH  - Echocardiography
MH  - Electrocardiography
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Septal Defects, Atrial/*surgery
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Postoperative Complications/epidemiology
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2008/11/06 09:00
MHDA- 2009/02/20 09:00
CRDT- 2008/11/06 09:00
PHST- 2008/11/06 09:00 [pubmed]
PHST- 2009/02/20 09:00 [medline]
PHST- 2008/11/06 09:00 [entrez]
PST - ppublish
SO  - Turk Kardiyol Dern Ars. 2008 Jul;36(5):287-93.