PMID- 18989557
OWN - NLM
STAT- MEDLINE
DCOM- 20090716
LR  - 20190917
IS  - 0104-4230 (Print)
IS  - 0104-4230 (Linking)
VI  - 54
IP  - 5
DP  - 2008 Sep-Oct
TI  - [Influence of hypertension on renal allograft survival in pediatric patients].
PG  - 396-9
LID - S0104-42302008000500010 [pii]
AB  - BACKGROUND: To evaluate the effect of 1 year systemic arterial hypertension on 
      3-year allograft survival in children with kidney transplantation. METHODS: A 
      retrospective study was carried out of pediatric patients submitted to kidney 
      transplantation at the Universidade Federal de Sao Paulo (UNIFESP) between 
      January, 1998 and January, 2003. Patients were classified as normotensive or 
      hypertensive according to presence of hypertension within the first year after 
      transplantation. Survival analyses were performed with the Kaplan-Meier survival 
      method, and survival curves were compared with the log-rank test. A p value of < 
      0.05 was considered statistically significant. RESULTS: Prior to transplantation 
      there were 86 patients (64%) and after 1 year, 70 children (52%) were classified 
      as hypertensive, respectively. Overall, the 3-year graft survival was of 92.5%. 
      Survival of the normotensive group was 95.3% and 90.0% for the hypertensive 
      group; the difference was not statistically significant. CONCLUSION: Although the 
      difference between the two groups was not statistically significant the higher 
      survival of the normotensive group seems to be clinically significant and allows 
      hypothesizing that arterial hypertension could be a risk factor for pediatric 
      graft survival. However, due to limitations of the study it is impossible to 
      affirm that hypertension is an independent risk factor for lower graft survival.
FAU - Nagasako, Samantha Santiago
AU  - Nagasako SS
AD  - Hospital do Rim e Hipertensao, Sao Paulo, SP.
FAU - Nogueira, Paulo Cesar Koch
AU  - Nogueira PC
FAU - Machado, Paula G P
AU  - Machado PG
FAU - Pestana, Jose O Medina
AU  - Pestana JO
LA  - por
PT  - English Abstract
PT  - Journal Article
TT  - Influencia da hipertensao na sobrevida do enxerto renal em pacientes pediatricos.
PL  - Brazil
TA  - Rev Assoc Med Bras (1992)
JT  - Revista da Associacao Medica Brasileira (1992)
JID - 9308586
SB  - IM
MH  - Adolescent
MH  - Brazil/epidemiology
MH  - Child
MH  - Child, Preschool
MH  - Epidemiologic Methods
MH  - *Graft Survival
MH  - Humans
MH  - Hypertension/*complications/diagnosis/epidemiology/etiology
MH  - *Kidney Transplantation
MH  - Risk Factors
MH  - Time Factors
MH  - Transplantation, Homologous
EDAT- 2008/11/08 09:00
MHDA- 2009/07/17 09:00
CRDT- 2008/11/08 09:00
PHST- 2007/05/03 00:00 [received]
PHST- 2008/03/26 00:00 [accepted]
PHST- 2008/11/08 09:00 [pubmed]
PHST- 2009/07/17 09:00 [medline]
PHST- 2008/11/08 09:00 [entrez]
AID - S0104-42302008000500010 [pii]
AID - 10.1590/s0104-42302008000500010 [doi]
PST - ppublish
SO  - Rev Assoc Med Bras (1992). 2008 Sep-Oct;54(5):396-9. doi: 
      10.1590/s0104-42302008000500010.