PMID- 18990397
OWN - NLM
STAT- MEDLINE
DCOM- 20090219
LR  - 20081125
IS  - 0021-9673 (Print)
IS  - 0021-9673 (Linking)
VI  - 1213
IP  - 2
DP  - 2008 Dec 12
TI  - Purge-assisted headspace solid-phase microextraction combined with gas 
      chromatography-mass spectrometry for determination of chlorophenols in aqueous 
      samples.
PG  - 245-8
LID - 10.1016/j.chroma.2008.10.056 [doi]
AB  - A simple, economical and very effective method is demonstrated for simultaneous 
      determination of 2,4-dichlorophenol, 2,4,6-trichlorophenol, 
      2,3,4,6-tetrachlorophenol and pentachlorophenol, in aqueous samples, by using 
      purge-assisted headspace solid-phase microextraction (PA/HS-SPME) coupled to gas 
      chromatography-mass spectrometry (GC-MS). In the new method, purging the sample 
      enhances the removal of the trace chlorophenols without derivatization from the 
      matrices to the headspace. Extraction parameters including extraction 
      temperature, purge gas flow rate and extraction time were systematically 
      investigated. Under optimal conditions, the relative standard deviations (RSDs) 
      were 4-11% at 50 pg/mL and 5-14% at 5 pg/mL, respectively. The recoveries were in 
      the range of 83-114%. Detection limits were determined at the fg level. These 
      results indicate that PA/HS-SPME provides a significant contribution to highly 
      efficient extraction of semi-volatile CPs, especially for pentachlorophenol, 
      which has the smallest Henry's constant and large octanol-water partitioning 
      coefficient. In addition, the proposed method was successfully applied to the 
      analysis of chlorophenols in landfill leachate. New perspectives are opened for 
      headspace extraction of relatively low vapor pressure compounds in complex 
      matrices.
FAU - Ho, Hsin-Pin
AU  - Ho HP
AD  - Department of Chemistry, National Chung Hsing University, Taichung 40227, Taiwan.
FAU - Lee, Ren-Jye
AU  - Lee RJ
FAU - Lee, Maw-Rong
AU  - Lee MR
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20081019
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Chlorophenols)
RN  - 0 (Water Pollutants, Chemical)
SB  - IM
MH  - Chlorophenols/*analysis
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Reproducibility of Results
MH  - Solid Phase Microextraction/instrumentation/*methods
MH  - Uncertainty
MH  - Water Pollutants, Chemical/*analysis
EDAT- 2008/11/08 09:00
MHDA- 2009/02/20 09:00
CRDT- 2008/11/08 09:00
PHST- 2008/03/18 00:00 [received]
PHST- 2008/10/08 00:00 [revised]
PHST- 2008/10/15 00:00 [accepted]
PHST- 2008/11/08 09:00 [pubmed]
PHST- 2009/02/20 09:00 [medline]
PHST- 2008/11/08 09:00 [entrez]
AID - S0021-9673(08)01838-4 [pii]
AID - 10.1016/j.chroma.2008.10.056 [doi]
PST - ppublish
SO  - J Chromatogr A. 2008 Dec 12;1213(2):245-8. doi: 10.1016/j.chroma.2008.10.056. 
      Epub 2008 Oct 19.