PMID- 1900096
OWN - NLM
STAT- MEDLINE
DCOM- 19910404
LR  - 20131121
IS  - 0195-9131 (Print)
IS  - 0195-9131 (Linking)
VI  - 23
IP  - 1
DP  - 1991 Jan
TI  - Influence of muscle glycogen depletion on the rate of resynthesis.
PG  - 44-8
AB  - In an effort to determine what effect the degree of muscle glycogen depletion has 
      on the rate of resynthesis, six male cyclists completed an exercise protocol that 
      involved both one- and two-legged cycling. One leg completed 30 min of single-leg 
      cycling, ten one-min sprints, and 30 min cycling with both legs. This resulted in 
      a large degree of depletion (LD). The contralateral leg completed only 30 min of 
      double-leg cycling and experienced a small amount of depletion (SD). Following 
      the exercise, the subjects rested quietly for 6 h and were fed a 24% carbohydrate 
      (CHO) solution every 20 min in order to achieve a CHO intake of 0.7 g.kg-1.h-1. 
      Biopsies taken from the vastus lateralis muscle immediately after exercise 
      revealed that the glycogen content of the LD leg decreased 93.9 (+/- 11.6) 
      mmol.kg-1 w.w., whereas the SD leg used 49.3 (+/- 5.7) mmol.kg-1 w.w. (P less 
      than 0.01). Subsequent biopsies taken at 2 and 6 h of recovery demonstrated that 
      the rate of muscle glycogen resynthesis was significantly greater in the LD leg, 
      averaging 8.8 (+/- 2.4) mmol.kg-1.h1 w.w, while the SD leg restored glycogen at a 
      rate of 3.0 (+/- 1.0) mmol.kg-1.h-1 w.w. (P less than 0.05). Glycogen synthase 
      activity, expressed as its activity ratio (I/D), was also greater (P less than 
      0.01) in the LD leg both immediately after exercise (0.45 +/- 0.05 vs 0.24 +/- 
      0.04) and at 2 h of recovery (0.54 +/- 0.06 vs 0.27 +/- 0.06).(ABSTRACT TRUNCATED 
      AT 250 WORDS)
FAU - Zachwieja, J J
AU  - Zachwieja JJ
AD  - Human Performance Laboratory, Ball State University, Muncie, IN 47306.
FAU - Costill, D L
AU  - Costill DL
FAU - Pascoe, D D
AU  - Pascoe DD
FAU - Robergs, R A
AU  - Robergs RA
FAU - Fink, W J
AU  - Fink WJ
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Med Sci Sports Exerc
JT  - Medicine and science in sports and exercise
JID - 8005433
RN  - 0 (Blood Glucose)
RN  - 0 (Lactates)
RN  - 33X04XA5AT (Lactic Acid)
RN  - EC 2.4.1.11 (Glycogen Synthase)
SB  - IM
MH  - Adult
MH  - Analysis of Variance
MH  - Blood Glucose/metabolism
MH  - Exercise/*physiology
MH  - Glycogen Synthase/*biosynthesis/metabolism
MH  - Humans
MH  - Lactates/blood
MH  - Lactic Acid
MH  - Leg
MH  - Male
MH  - Muscles/*metabolism
MH  - Phosphorylation
EDAT- 1991/01/01 00:00
MHDA- 1991/01/01 00:01
CRDT- 1991/01/01 00:00
PHST- 1991/01/01 00:00 [pubmed]
PHST- 1991/01/01 00:01 [medline]
PHST- 1991/01/01 00:00 [entrez]
PST - ppublish
SO  - Med Sci Sports Exerc. 1991 Jan;23(1):44-8.