PMID- 19004666 OWN - NLM STAT- MEDLINE DCOM- 20090311 LR - 20110608 IS - 1388-9842 (Print) IS - 1388-9842 (Linking) VI - 10 IP - 12 DP - 2008 Dec TI - Successful treatment of heart failure with devices requires collaboration. PG - 1229-35 LID - 10.1016/j.ejheart.2008.09.015 [doi] AB - Implanted biventricular pacemakers (cardiac resynchronisation therapy, CRT) with or without implantable cardioverter defibrillators (ICD) improve survival and morbidity in some patients with chronic heart failure (CHF) who are optimally treated with pharmacologic agents according to current guidelines. Correspondingly, ICDs improve survival. However, there is only limited evidence for device treatment in certain patient subgroups, such as the impact of ICD on outcomes in patients with reduced ejection fraction in New York Heart Association (NYHA) Class I or IV heart failure. Similarly, limited evidence exists for CRT in patients with only modest QRS prolongation or only modestly reduced ejection fraction. Despite evidence for a beneficial effect of device therapy in CHF, only a minority of eligible patients are currently offered these options. Multiple reasons contribute to the underuse of these potentially life-saving therapies. A lack of adherence to guidelines by health care professionals is an important barrier. Clearly, efforts should be made to improve the standard of care and to familiarise all physicians involved in managing CHF patients with the indications and potential efficacy of these devices. Increased collaboration between structured heart failure care and pacemaker clinics as well as between electrophysiologists, heart failure clinicians, and primary care physicians is required. Such team collaborations should lead to improved care with reduced mortality and morbidity and increased cost effectiveness. Treatment strategy should be based on a structured approach tailored to local practice and national priorities. FAU - Swedberg, Karl AU - Swedberg K AD - Department of Emergency and Cardiovascular Medicine, Sahlgrenska Academy, University of Gothenburg, Goteborg, Sweden. karl.swedberg@gu.se FAU - Cleland, John AU - Cleland J FAU - Cowie, Martin R AU - Cowie MR FAU - Nieminen, Markku AU - Nieminen M FAU - Priori, Silvia G AU - Priori SG FAU - Tavazzi, Luigi AU - Tavazzi L FAU - van Veldhuisen, Dirk J AU - van Veldhuisen DJ FAU - Alonso-Pulpon, Luis AU - Alonso-Pulpon L FAU - Camm, John AU - Camm J FAU - Dickstein, Kenneth AU - Dickstein K FAU - Drexler, Helmut AU - Drexler H FAU - Filippatos, Gerasimos AU - Filippatos G FAU - Linde, Cecilia AU - Linde C FAU - Lopez-Sendon, Jose AU - Lopez-Sendon J FAU - Santini, Massimo AU - Santini M FAU - Zannad, Faiez AU - Zannad F LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review DEP - 20081112 PL - England TA - Eur J Heart Fail JT - European journal of heart failure JID - 100887595 SB - IM MH - *Cardiac Pacing, Artificial MH - Chronic Disease MH - *Cooperative Behavior MH - Heart Failure/mortality/physiopathology/*therapy MH - Humans MH - *Pacemaker, Artificial MH - Stroke Volume MH - Time Factors MH - Ventricular Function, Left RF - 29 EDAT- 2008/11/14 09:00 MHDA- 2009/03/12 09:00 CRDT- 2008/11/14 09:00 PHST- 2008/08/11 00:00 [received] PHST- 2008/09/22 00:00 [accepted] PHST- 2008/11/14 09:00 [pubmed] PHST- 2009/03/12 09:00 [medline] PHST- 2008/11/14 09:00 [entrez] AID - S1388-9842(08)00458-3 [pii] AID - 10.1016/j.ejheart.2008.09.015 [doi] PST - ppublish SO - Eur J Heart Fail. 2008 Dec;10(12):1229-35. doi: 10.1016/j.ejheart.2008.09.015. Epub 2008 Nov 12.