PMID- 19008366
OWN - NLM
STAT- MEDLINE
DCOM- 20090717
LR  - 20081114
IS  - 1470-2738 (Electronic)
IS  - 0143-005X (Linking)
VI  - 62
IP  - 12
DP  - 2008 Dec
TI  - Incidence of adverse events related to health care in Spain: results of the 
      Spanish National Study of Adverse Events.
PG  - 1022-9
LID - 10.1136/jech.2007.065227 [doi]
AB  - OBJECTIVE: To determine the incidence and incidence density of adverse events 
      (AEs) in Spanish hospitals (including the pre-hospitalisation period). METHOD: 
      Retrospective cohort study. RESULTS: The incidence of patients with AEs relating 
      directly to hospital care was 8.4% (95% CI 7.7% to 9.1%) and rose 9.3% (95% CI 
      8.6% to 10.1%), including those from the pre-hospitalisation period. The 
      incidence density was 1.2 AEs per 100 patient-days (95% CI 1.1 to 1.3). The 
      incidence of moderate and serious AEs was 5.6 AEs per 1000 patient-days (95% CI 
      4.9% to 6.3%). In 66.3% of AEs, additional procedures were required and in 69.9% 
      additional treatments were required. In total 42.8% of AEs were considered as 
      avoidable. Of the subjects with some intrinsic risk factors, 13.2% developed AEs 
      compared with 5.2% of the subjects who had no risk factors (p<0.001), and 9.5% of 
      the subjects who had some extrinsic risk factors developed AEs compared with 3.4% 
      of the subjects who had not (p<0.001). Patients older than 65 years of age showed 
      a higher frequency of AEs than those under this age (12.4% vs 5.4%, p<0.001, RR 
      2.5). The most frequent AEs were those associated with medication (37.4%), 
      hospital infections of any type (25.3%) and those relating to technical problems 
      during a procedure (25.0%). A total of 31.4% of the AEs involved an increase in 
      the length of stay. The AEs associated with medical assistance caused 6.1 
      additional hospital stays by patient. CONCLUSIONS: The incidence of patients with 
      AE related to medical assistance in Spanish hospitals was relevant and similar to 
      those found in the studies from Canada and New Zealand that had been conducted 
      with comparable methodology. Patient vulnerability has been identified therein as 
      playing a major role in generating healthcare-related AEs. These and other recent 
      results indicate the need for AEs to be considered a public health priority in 
      Europe.
FAU - Aranaz-Andres, J M
AU  - Aranaz-Andres JM
AD  - Department of Preventive Medicine, Teaching Hospital of Sant Joan d'Alacant, 
      Spain. aranaz_jes@gva.es
FAU - Aibar-Remon, C
AU  - Aibar-Remon C
FAU - Vitaller-Murillo, J
AU  - Vitaller-Murillo J
FAU - Ruiz-Lopez, P
AU  - Ruiz-Lopez P
FAU - Limon-Ramirez, R
AU  - Limon-Ramirez R
FAU - Terol-Garcia, E
AU  - Terol-Garcia E
CN  - ENEAS work group
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - J Epidemiol Community Health
JT  - Journal of epidemiology and community health
JID - 7909766
SB  - IM
MH  - Age Factors
MH  - Aged
MH  - Cohort Studies
MH  - Delivery of Health Care/*statistics & numerical data
MH  - Health Facility Size
MH  - Hospitalization/*statistics & numerical data
MH  - Humans
MH  - Iatrogenic Disease/*epidemiology
MH  - Incidence
MH  - Length of Stay
MH  - Medical Audit
MH  - Medical Errors/*statistics & numerical data
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Spain/epidemiology
EDAT- 2008/11/15 09:00
MHDA- 2009/07/18 09:00
CRDT- 2008/11/15 09:00
PHST- 2008/11/15 09:00 [pubmed]
PHST- 2009/07/18 09:00 [medline]
PHST- 2008/11/15 09:00 [entrez]
AID - 62/12/1022 [pii]
AID - 10.1136/jech.2007.065227 [doi]
PST - ppublish
SO  - J Epidemiol Community Health. 2008 Dec;62(12):1022-9. doi: 
      10.1136/jech.2007.065227.