PMID- 19011275
OWN - NLM
STAT- MEDLINE
DCOM- 20090804
LR  - 20090507
IS  - 1421-9670 (Electronic)
IS  - 0250-8095 (Linking)
VI  - 29
IP  - 5
DP  - 2009
TI  - Prognostic utility of impedance cardiography measurements in elderly hemodialysis 
      patients with coronary artery disease.
PG  - 426-33
LID - 10.1159/000174855 [doi]
AB  - AIM: We evaluated the utility of impedance cardiography (IC) in elderly 
      hemodialysis (HD) patients with coronary artery disease (CAD). PATIENTS AND 
      METHODS: Seventy-five HD patients (30 with CAD) participated. IC cardiac output 
      (ICCO), systemic vascular resistance and pulse pressure (PP) were calculated at 
      baseline, and 30 and 180 days after study entry. ICCO was compared to 
      echocardiography cardiac output (ECO). Relationships of IC measurements and 
      cardiovascular mortality were assessed. Patients were followed up for 6 years 
      after study entry or until death due to cardiovascular events. RESULTS: ICCO and 
      ECO were strongly correlated (r = 0.94, p < 0.001). ICCO correlated inversely 
      with PP (r = -0.61; p < 0.001). Thirty fatal cardiovascular events were recorded. 
      Using the bayesian' information criterion, multivariate Cox regression models 
      revealed that increased PP and New York Heart Association (NYHA) class as well as 
      decreased diastolic blood pressure (DBP) were predictors of cardiovascular 
      mortality. Having a DBP <60 mm Hg (adjusted for NYHA) yielded a hazard ratio of 
      2.8 (95% confidence interval = 1.2-6.7). CONCLUSION: IC accurately estimates the 
      hemodynamic status in HD patients with CAD. Deterioration of cardiovascular 
      performance expressed by decreased DBP values, adjusted for NYHA, may help to 
      predict outcome.
CI  - Copyright (c) 2008 S. Karger AG, Basel.
FAU - Karakitsos, Dimitrios
AU  - Karakitsos D
AD  - Division of Biostatistics, Texas Tech University Health Sciences Center, Lubbock, 
      TX, USA.
FAU - Wachtel, Mitchell
AU  - Wachtel M
FAU - Zerefos, Nicolaos
AU  - Zerefos N
FAU - Valis, Dimitrios
AU  - Valis D
FAU - Patrianakos, Alexandros
AU  - Patrianakos A
FAU - Saranteas, Theodosios
AU  - Saranteas T
FAU - Daphnis, Eugene
AU  - Daphnis E
FAU - Boletis, John
AU  - Boletis J
FAU - Stefanadis, Christodoulos
AU  - Stefanadis C
FAU - Karabinis, Andreas
AU  - Karabinis A
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Multicenter Study
DEP - 20081114
PL  - Switzerland
TA  - Am J Nephrol
JT  - American journal of nephrology
JID - 8109361
SB  - IM
MH  - Aged
MH  - Blood Pressure
MH  - *Cardiac Output
MH  - Cardiography, Impedance
MH  - Coronary Artery Disease/complications/*diagnosis/mortality
MH  - Echocardiography
MH  - Female
MH  - Humans
MH  - Kidney Failure, Chronic/*complications
MH  - Male
MH  - Prognosis
MH  - Renal Dialysis
MH  - Survival Analysis
MH  - Vascular Resistance
EDAT- 2008/11/18 09:00
MHDA- 2009/08/06 09:00
CRDT- 2008/11/18 09:00
PHST- 2008/08/02 00:00 [received]
PHST- 2008/09/24 00:00 [accepted]
PHST- 2008/11/18 09:00 [pubmed]
PHST- 2009/08/06 09:00 [medline]
PHST- 2008/11/18 09:00 [entrez]
AID - 000174855 [pii]
AID - 10.1159/000174855 [doi]
PST - ppublish
SO  - Am J Nephrol. 2009;29(5):426-33. doi: 10.1159/000174855. Epub 2008 Nov 14.