PMID- 19012209 OWN - NLM STAT- MEDLINE DCOM- 20090226 LR - 20081117 IS - 0171-6425 (Print) IS - 0171-6425 (Linking) VI - 56 IP - 8 DP - 2008 Dec TI - Tricuspid valve replacement: an analysis of risk factors and outcomes. PG - 456-60 LID - 10.1055/s-2008-1038730 [doi] AB - BACKGROUND: Tricuspid valve replacement (TVR) is rarely performed and is associated with a high morbidity and mortality. We report our experience with TVR and related adverse events. METHODS: Between January 1996 and December 2007, 35 patients underwent TVR with mechanical (n = 33) or bioprosthetic (n = 2) valves. Twenty-nine patients underwent concomitant cardiac procedures. RESULTS: All patients completed follow-up (mean 47 months). Thirty-day mortality was 20 % (n = 7). Risk factors included perioperative low arterial blood pressure ( P = 0.000), New York Heart Association (NYHA) functional class III or IV ( P = 0.001), severe pulmonary hypertension (pulmonary arterial pressure greater than 60 mmHg) ( P = 0.000), hepatic dysfunction ( P = 0.000), ascites ( P = 0.003), and reoperation ( P = 0.015). Late mortality occurred in five patients. Valve-related complications included bleeding (n = 1) and stroke (n = 1). Kaplan-Meier estimates of 1-, 5- and 10-year survival (including early mortality) and event-free survival were 77.1 %, 60 %, and 54.3 % and 91.1 %, 80.6 %, and 55.9 %, respectively. Severe pulmonary hypertension was the only predictor of late mortality ( P = 0.001). Among survivors, the mean NYHA class improved from 2.8 to 1.1 ( P = 0.000). CONCLUSIONS: Although early outcome after TVR is suboptimal, long-term survival and functional improvement is satisfactory. FAU - Civelek, A AU - Civelek A AD - Department o Cardiovascular Surgery, Marmara University School of Medicine, Istanbul, Turkey. alicivelek@tnn.net FAU - Ak, K AU - Ak K FAU - Akgun, S AU - Akgun S FAU - Isbir, S C AU - Isbir SC FAU - Arsan, S AU - Arsan S LA - eng PT - Journal Article DEP - 20081114 PL - Germany TA - Thorac Cardiovasc Surg JT - The Thoracic and cardiovascular surgeon JID - 7903387 SB - IM MH - Ascites/complications MH - Bioprosthesis MH - Blood Pressure MH - Female MH - Follow-Up Studies MH - *Heart Valve Prosthesis MH - Heart Valve Prosthesis Implantation/mortality MH - Humans MH - Hypertension, Pulmonary/complications MH - Liver Diseases/complications MH - Male MH - Reoperation MH - Risk Factors MH - *Tricuspid Valve EDAT- 2008/11/18 09:00 MHDA- 2009/02/27 09:00 CRDT- 2008/11/18 09:00 PHST- 2008/11/18 09:00 [pubmed] PHST- 2009/02/27 09:00 [medline] PHST- 2008/11/18 09:00 [entrez] AID - 10.1055/s-2008-1038730 [doi] PST - ppublish SO - Thorac Cardiovasc Surg. 2008 Dec;56(8):456-60. doi: 10.1055/s-2008-1038730. Epub 2008 Nov 14.