PMID- 19016146 OWN - NLM STAT- MEDLINE DCOM- 20090203 LR - 20101118 IS - 1525-6049 (Electronic) IS - 0886-022X (Linking) VI - 30 IP - 10 DP - 2008 TI - Clinical outcome following the use of inadequate solutions for continuous veno-venous hemodiofiltration. PG - 959-64 LID - 10.1080/08860220802422028 [doi] AB - BACKGROUND: A short time ago, commercially available diafiltration and replacement fluids could be found o n the hospital in Turkey. Instead, peritoneal dialysis solution (PDS) for continue veno-venous hemodiafiltration (CVVHDF) therapy and normal saline as replacement fluid are used. In this retrospective study, we investigated the effects of PDS and bicarbonate-buffered hemofiltration solution (Bic-HFS). METHODS: We did a retrospective chart review of 24 patients treated with continue renal replacement therapy (CRRT) between January 2004 and February 2008. Peritoneal dialysis solution (PDS) was used in 14 patients, and bicarbonate-buffered hemodialysis solution (bic-HFS) was used in 10 patients. RESULTS: Demographic data, laboratory findings, and mortality rate were similar both groups. Blood glucose and lactate levels were higher in the PD group than the bic-HFS group (p < 0.05). Hyperglycemia occurred more frequent in the PDS group than in the bic-HFS group (64% versus 30%, respectively; p < 0.05). Metabolic acidosis occurred in eight patients (57%) in the PDS group and three patients (30%) in the bic-HFS group (p < 0.05). Hypotension was higher in the PDS group (10, 71%) than in the bic-HFS group (3, 30%; p < 0.05). CONCLUSION: Using PDS fluid as dialysate for CVVHDF therapy is not a preferable solution because of the metabolic disturbances that it can cause. FAU - Celik, Jale Bengi AU - Celik JB AD - Meram Medicine Faculty, Department of Anaesthesiology, Selcuk University, Konya, Turkey. jalecelik@hotmail.com FAU - Topal, Ahmet AU - Topal A FAU - Kartal, Elmas AU - Kartal E FAU - Yosunkaya, Alper AU - Yosunkaya A LA - eng PT - Comparative Study PT - Journal Article PL - England TA - Ren Fail JT - Renal failure JID - 8701128 RN - 0 (Dialysis Solutions) SB - IM MH - Acidosis/*etiology MH - Acute Kidney Injury/complications/*therapy MH - Aged MH - Dialysis Solutions/*adverse effects/standards MH - Female MH - *Hemodiafiltration MH - Humans MH - Hyperglycemia/etiology MH - Male MH - Middle Aged MH - Retrospective Studies MH - Treatment Outcome EDAT- 2008/11/19 09:00 MHDA- 2009/02/04 09:00 CRDT- 2008/11/19 09:00 PHST- 2008/11/19 09:00 [pubmed] PHST- 2009/02/04 09:00 [medline] PHST- 2008/11/19 09:00 [entrez] AID - 905629592 [pii] AID - 10.1080/08860220802422028 [doi] PST - ppublish SO - Ren Fail. 2008;30(10):959-64. doi: 10.1080/08860220802422028.