PMID- 19018552 OWN - NLM STAT- MEDLINE DCOM- 20090325 LR - 20220408 IS - 1435-702X (Electronic) IS - 0721-832X (Linking) VI - 247 IP - 3 DP - 2009 Mar TI - Spectral-domain optical coherence tomography images of inner/outer segment junctions and macular hole surgery outcomes. PG - 325-30 LID - 10.1007/s00417-008-0999-9 [doi] AB - BACKGROUND: To evaluate the ability of spectral-domain optical coherence tomography (SD-OCT) images of the inner/outer segment (IS/OS) junction to predict macular hole surgery outcomes. METHODS: Fifty-four eyes in 53 patients with idiopathic macular holes were studied. Postoperative visual acuity and SD-OCT images of the fovea were examined before and 12 months after surgery. The total area and the maximum length of the IS/OS junction defect were measured. RESULTS: The macular holes were successfully closed in all the eyes included in this series. The mean log MAR visual acuity improved significantly from 0.67 +/- 0.25 preoperatively to 0.16 +/- 0.22 postoperatively (p < 0.001). The mean total area and maximum length of the IS/OS junction defect at 12 months after surgery were 10,185 +/- 1,537 microm(2) and 100.5 +/- 10.4 microm respectively; these values were significantly negatively correlated with the postoperative visual acuity. CONCLUSION: SD-OCT is useful for quantitatively measuring IS/OS junction defects. The postoperative IS/OS junction may play an important role in visual recovery after macular hole surgery. FAU - Inoue, Maiko AU - Inoue M AD - Department of Ophthalmology, Yokohama City University Medical Center, Yokohama, Japan. maicoo@urahp.yokohama-cu.ac.jp FAU - Watanabe, Yoichiro AU - Watanabe Y FAU - Arakawa, Akira AU - Arakawa A FAU - Sato, Shimpei AU - Sato S FAU - Kobayashi, Satoshi AU - Kobayashi S FAU - Kadonosono, Kazuaki AU - Kadonosono K LA - eng PT - Journal Article DEP - 20081119 PL - Germany TA - Graefes Arch Clin Exp Ophthalmol JT - Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie JID - 8205248 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Female MH - Humans MH - Male MH - Middle Aged MH - Retinal Perforations/*diagnosis/*surgery MH - Retinal Photoreceptor Cell Inner Segment/*pathology MH - Retinal Photoreceptor Cell Outer Segment/*pathology MH - Tomography, Optical Coherence/*methods MH - Treatment Outcome MH - Visual Acuity/physiology EDAT- 2008/11/20 09:00 MHDA- 2009/03/26 09:00 CRDT- 2008/11/20 09:00 PHST- 2008/09/10 00:00 [received] PHST- 2008/10/29 00:00 [accepted] PHST- 2008/10/18 00:00 [revised] PHST- 2008/11/20 09:00 [pubmed] PHST- 2009/03/26 09:00 [medline] PHST- 2008/11/20 09:00 [entrez] AID - 10.1007/s00417-008-0999-9 [doi] PST - ppublish SO - Graefes Arch Clin Exp Ophthalmol. 2009 Mar;247(3):325-30. doi: 10.1007/s00417-008-0999-9. Epub 2008 Nov 19.