PMID- 19031024
OWN - NLM
STAT- MEDLINE
DCOM- 20090219
LR  - 20081125
IS  - 0171-2004 (Print)
IS  - 0171-2004 (Linking)
IP  - 188
DP  - 2009
TI  - Dendritic cells in rhinitis.
PG  - 115-36
LID - 10.1007/978-3-540-71029-5_6 [doi]
AB  - Dendritic cells (DCs) play an important role in all kind of rhinitis and 
      sinusitis. One of the most important upper airway diseases is allergic rhinitis. 
      DCs are the professional antigen presenting cells that have the capacity to 
      present antigen to naive-T cells and T-effector cells. In the context of a broad 
      spectrum of rhinitis, from allergic rhinitis via upper respiratory tract virus 
      infection to chronic sinusitis, DCs have an important role in the immunological 
      outcome of the disease. Studies in humans and animal models that have highlighted 
      the role of DC were evaluated. This article reviews recent information on the 
      involvement of DC in rhinitis, and the mechanisms by which DC could be employed 
      as targets for therapeutic intervention.
FAU - Kleinjan, Alex
AU  - Kleinjan A
AD  - Department of Pulmonary Medicine, Erasmus M.C, Dr. Molerwaterplein, Rotterdam, 
      The Netherlands. a.kleinjan@erasmusmc.nl
FAU - Lambrecht, Bart N
AU  - Lambrecht BN
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Germany
TA  - Handb Exp Pharmacol
JT  - Handbook of experimental pharmacology
JID - 7902231
RN  - 0 (Chemokines)
RN  - 0 (Cytokines)
SB  - IM
MH  - Animals
MH  - Antigen Presentation
MH  - Cell Movement
MH  - Chemokines/metabolism
MH  - Cytokines/metabolism
MH  - Dendritic Cells/drug effects/*immunology
MH  - Dendritic Cells, Follicular/immunology
MH  - Disease Models, Animal
MH  - Humans
MH  - Immune Tolerance
MH  - Immunity, Mucosal
MH  - Immunotherapy/methods
MH  - Langerhans Cells/immunology
MH  - Nasal Mucosa/immunology
MH  - Rhinitis/*immunology/therapy
RF  - 98
EDAT- 2008/11/26 09:00
MHDA- 2009/02/20 09:00
CRDT- 2008/11/26 09:00
PHST- 2008/11/26 09:00 [pubmed]
PHST- 2009/02/20 09:00 [medline]
PHST- 2008/11/26 09:00 [entrez]
AID - 10.1007/978-3-540-71029-5_6 [doi]
PST - ppublish
SO  - Handb Exp Pharmacol. 2009;(188):115-36. doi: 10.1007/978-3-540-71029-5_6.