PMID- 19046277
OWN - NLM
STAT- MEDLINE
DCOM- 20090227
LR  - 20181201
IS  - 1463-5224 (Electronic)
IS  - 1463-5216 (Linking)
VI  - 11
IP  - 6
DP  - 2008 Nov-Dec
TI  - Review of the measuring precision of the new Meibometer MB550 through repeated 
      measurements in dogs.
PG  - 368-74
LID - 10.1111/j.1463-5224.2008.00660.x [doi]
AB  - OBJECTIVE: A meibometer is a device to measure the delivery rate of lipids on the 
      eyelid margin. The aim of this study is to determine the measuring precision of 
      the new Meibometer MB550 (Courage-Khazaka electronic GmbH, 50829, Cologne, 
      Germany), linked to a computer, by means of repeated measurements in dogs by 
      different examiners. PROCEDURE: Two investigators measured the lipid rate on the 
      eyelid margin in 10 healthy dogs for 10 days. One examiner measured the right eye 
      (OD) and the other measured the left eye (OS) for 5 days. After 5 days, the eyes 
      to be measured were switched between the examiners. The new device was able to 
      record all measurement values as charts and curves in comparison to the previous 
      Meibometer, which displayed only one value. RESULTS: Mean meibomium lipid level 
      +/- SD in the OD and OS of 10 dogs in 10 days was 211 +/- 48 MU and 205 +/- 41 MU 
      (meibometer units), respectively. There was no significant difference between OD 
      and OS, but a broad distribution of the values could be found. Gender did not 
      influence the measurements. A significant difference was determined between the 
      measurements in the first 5 days to those in the following 5 days. There was, 
      therefore, also a significant difference in the measurements of the 2 examiners. 
      CONCLUSION: Meibometry is a minimally invasive lipid measuring method on the 
      eyelid margin. Repeated measurement results obtained by two examiners, with the 
      new device Meibometer MB550 linked to a computer, showed a wide range of values. 
      The measuring precision of the new Meibometer MB550 is therefore questionable.
FAU - Benz, Petra
AU  - Benz P
AD  - Department of small animals and horses, Veterinary University Vienna, Vienna, 
      Austria. petra.benz@vu-wien.ac.at
FAU - Tichy, Alexander
AU  - Tichy A
FAU - Nell, Barbara
AU  - Nell B
LA  - eng
PT  - Journal Article
PL  - England
TA  - Vet Ophthalmol
JT  - Veterinary ophthalmology
JID - 100887377
RN  - 0 (Lipids)
SB  - IM
MH  - Animals
MH  - Diagnostic Techniques, Ophthalmological/instrumentation/standards/*veterinary
MH  - Dog Diseases/diagnosis/metabolism
MH  - Dogs/*metabolism
MH  - Dry Eye Syndromes/diagnosis/metabolism/veterinary
MH  - Eyelids/metabolism
MH  - Female
MH  - Image Interpretation, Computer-Assisted
MH  - *Lipid Metabolism
MH  - Male
MH  - Meibomian Glands/*metabolism
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
EDAT- 2008/12/03 09:00
MHDA- 2009/02/28 09:00
CRDT- 2008/12/03 09:00
PHST- 2008/12/03 09:00 [pubmed]
PHST- 2009/02/28 09:00 [medline]
PHST- 2008/12/03 09:00 [entrez]
AID - VOP660 [pii]
AID - 10.1111/j.1463-5224.2008.00660.x [doi]
PST - ppublish
SO  - Vet Ophthalmol. 2008 Nov-Dec;11(6):368-74. doi: 10.1111/j.1463-5224.2008.00660.x.