PMID- 19049064
OWN - NLM
STAT- MEDLINE
DCOM- 20081219
LR  - 20190715
IS  - 1533-4880 (Print)
IS  - 1533-4880 (Linking)
VI  - 8
IP  - 9
DP  - 2008 Sep
TI  - Microfabricated in-channel structured polydimethylsiloxane microfluidic system 
      for a lab-on-a-chip.
PG  - 4588-92
AB  - In this paper, the fabrication of microfluidic system integrated with micropump 
      and microvalve on the same substrate and its high performance are described. The 
      microfabricated microfluidic system has been optimized for application in 
      capillary electrophoresis-electrochemical detector (CE-ECD), polymerase chain 
      reaction (PCR) and microcantilever. The system is realized by means of a 
      polydimethylsiloxane (PDMS)-glass chip and indium tin oxide heater. The pumping 
      rates of the proposed micropump are measured as functions of the frequency and 
      the duty-ratio of applied voltage. The performances of the microvalves are 
      characterized under the on/off alternation with the applied power of the indium 
      tin oxide (ITO) heater. The flow rate gradually decreases as the applied heater 
      power increase. The optimized membrane thickness for microfluidic system is 350 
      microm. At this condition, the power of the cut-off flow in microvalve is 400 mW 
      and the 70 nl/min of maximum pumping rate is observed at a duty ratio of 4% and a 
      frequency of 4 Hz for the applied pulse power.
FAU - Ra, Gyu-Sik
AU  - Ra GS
AD  - Department of Nano Science and Engineering, Myongji University, Gyeonggi 449-728, 
      Korea.
FAU - Yoo, Jong-Chul
AU  - Yoo JC
FAU - Kang, C J
AU  - Kang CJ
FAU - Kim, Yong-Sang
AU  - Kim YS
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Nanosci Nanotechnol
JT  - Journal of nanoscience and nanotechnology
JID - 101088195
RN  - 0 (Dimethylpolysiloxanes)
RN  - 0 (Tin Compounds)
RN  - 63148-62-9 (baysilon)
RN  - 71243-84-0 (indium tin oxide)
SB  - IM
MH  - Dimethylpolysiloxanes/*chemistry
MH  - Electrochemistry/instrumentation
MH  - Electrophoresis, Microchip/instrumentation
MH  - Equipment Design
MH  - Microchemistry/*instrumentation
MH  - Microelectrodes
MH  - Microfluidic Analytical Techniques/instrumentation
MH  - Microfluidics/*instrumentation
MH  - Polymerase Chain Reaction
MH  - Protein Array Analysis
MH  - Tin Compounds/*chemistry
EDAT- 2008/12/04 09:00
MHDA- 2008/12/20 09:00
CRDT- 2008/12/04 09:00
PHST- 2008/12/04 09:00 [pubmed]
PHST- 2008/12/20 09:00 [medline]
PHST- 2008/12/04 09:00 [entrez]
AID - 10.1166/jnn.2008.ic83 [doi]
PST - ppublish
SO  - J Nanosci Nanotechnol. 2008 Sep;8(9):4588-92. doi: 10.1166/jnn.2008.ic83.