PMID- 19052335
OWN - NLM
STAT- MEDLINE
DCOM- 20090413
LR  - 20220410
IS  - 0971-5916 (Print)
IS  - 0971-5916 (Linking)
VI  - 128
IP  - 3
DP  - 2008 Sep
TI  - Effect of emotional stress on sperm quality.
PG  - 254-61
AB  - BACKGROUND & OBJECTIVE: Emotional stress plays a detrimental role on fertility. 
      In this study male patients with idiopathic infertility were selected after 
      evaluation of psychological stress to evaluate a positive effect of a stress 
      therapy on their semen quality. METHODS: A total of 20 patients with infertility 
      were enrolled in the study and randomly divided in two groups. Ejaculates were 
      examined by light and transmission electron microscopy (TEM). Meiotic segregation 
      was also investigated by fluorescence in situ hybridization (FISH). Ten patients 
      were treated with Conveyer of Modulating Radiance (CRM) therapy and sperm 
      characteristics and meiotic segregation were evaluated again three months at the 
      end of treatment. RESULTS: TEM data showed that, among sperm pathologies, 
      necrosis and apoptosis were higher and the number of "healthy" sperm was 
      significantly reduced in both groups of stressed men compared to reference 
      values. The number of "healthy" sperm was significantly higher in the treated 
      group after therapy, indicating a recovery of sperm quality, although no 
      significant decrease in sperm pathologies was observed. FISH analysis showed that 
      the mean frequencies of sex chromosomes disomies and diploidies significantly 
      decreased after stress therapy. INTERPRETATION & CONCLUSION: The effects induced 
      by stress also seem to include meiotic and structural alterations in sperm cells. 
      The spermatogenic process was improved after a cycle of CRM therapy indicating 
      that stress is an additional risk factor for idiopathic infertility.
FAU - Collodel, Giulia
AU  - Collodel G
AD  - Department of Surgery, Biology Section, Interdepartmental Centre for Research & 
      Therapy of Male Infertility, University of Siena, Italy. collodel@unisi.it
FAU - Moretti, Elena
AU  - Moretti E
FAU - Fontani, Vania
AU  - Fontani V
FAU - Rinaldi, Salvatore
AU  - Rinaldi S
FAU - Aravagli, Lucia
AU  - Aravagli L
FAU - Sarago, Giorgio
AU  - Sarago G
FAU - Capitani, Serena
AU  - Capitani S
FAU - Anichini, Cecilia
AU  - Anichini C
LA  - eng
PT  - Journal Article
PL  - India
TA  - Indian J Med Res
JT  - The Indian journal of medical research
JID - 0374701
SB  - IM
CIN - Indian J Med Res. 2008 Sep;128(3):228-30. PMID: 19052330
MH  - Adult
MH  - Affective Symptoms/*epidemiology
MH  - Apoptosis
MH  - Cell Nucleus/pathology
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - *Infertility, Male/epidemiology/pathology/psychology
MH  - Male
MH  - Microscopy, Electron, Transmission
MH  - Necrosis
MH  - Psychological Tests
MH  - Risk Factors
MH  - Sperm Motility
MH  - Spermatozoa/*pathology/ultrastructure
MH  - Stress, Psychological/*epidemiology
EDAT- 2008/12/05 09:00
MHDA- 2009/04/14 09:00
CRDT- 2008/12/05 09:00
PHST- 2008/12/05 09:00 [pubmed]
PHST- 2009/04/14 09:00 [medline]
PHST- 2008/12/05 09:00 [entrez]
PST - ppublish
SO  - Indian J Med Res. 2008 Sep;128(3):254-61.