PMID- 19052916
OWN - NLM
STAT- MEDLINE
DCOM- 20090828
LR  - 20211020
IS  - 1573-2649 (Electronic)
IS  - 0962-9343 (Linking)
VI  - 18
IP  - 1
DP  - 2009 Feb
TI  - Disease-specific health-related quality of life questionnaires for heart failure: 
      a systematic review with meta-analyses.
PG  - 71-85
LID - 10.1007/s11136-008-9416-4 [doi]
AB  - BACKGROUND: Heart failure (HF) is an increasingly common condition affecting 
      patients' health-related quality of life (HRQL). However, there is little 
      literature comparing HF-specific instruments. Our aim was to evaluate and compare 
      data on the conceptual model and metric properties (reliability, validity and 
      responsiveness) of HF-specific HRQL instruments, by performing a systematic 
      review with meta-analyses. METHODS AND RESULTS: Of 2,541 articles initially 
      identified, 421 were full-text reviewed. Ninety-four reported data on five 
      questionnaires: Minnesota Living with Heart Failure Questionnaire (MLHFQ), 
      Chronic Heart Failure Questionnaire (CHFQ), Quality of Life Questionnaire for 
      Severe Heart Failure (QLQ-SHF), Kansas City Cardiomyopathy Questionnaire (KCCQ) 
      and Left Ventricular Dysfunction (LVD-36) questionnaire. Metric properties 
      (reliability, validity and responsiveness) were summarised using meta-analysis 
      for pools above five estimates. Cronbach's alpha coefficients were generally high 
      (0.83-0.95) for overall scores and scales measuring physical health. Associations 
      with four validity criteria (New York Heart Association [NYHA] class, six-minute 
      walk test [6MWT] and short form-36 [SF-36] 'Physical' and 'Social Functioning') 
      were moderate to strong (0.41-0.84), except for those between two CHFQ domains 
      (fatigue and dyspnoea) and the NYHA (0.19 and 0.22). Pooled estimates of change 
      from eight meta-analyses showed the MLHFQ to be highly responsive, with changes 
      in overall score ranging from -9.6 (95% confidence interval [CI]: -4.1; -15.2) 
      for placebo to -17.7 (95% CI: -15.3; -20.2) for pacing devices. The CHFQ and KCCQ 
      also showed good sensitivity to change. CONCLUSIONS: Most of the questionnaires 
      studied met minimum psychometric criteria, though current evidence would 
      primarily support the use of the MLHFQ, followed by the KCCQ and CHFQ.
FAU - Garin, Olatz
AU  - Garin O
AD  - Health Services Research Unit, IMIM-Hospital del Mar, Doctor Aiguader 80, 08003, 
      Barcelona, Spain.
FAU - Ferrer, Montse
AU  - Ferrer M
FAU - Pont, Angels
AU  - Pont A
FAU - Rue, Montserrat
AU  - Rue M
FAU - Kotzeva, Anna
AU  - Kotzeva A
FAU - Wiklund, Ingela
AU  - Wiklund I
FAU - Van Ganse, Eric
AU  - Van Ganse E
FAU - Alonso, Jordi
AU  - Alonso J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PT  - Systematic Review
DEP - 20081204
PL  - Netherlands
TA  - Qual Life Res
JT  - Quality of life research : an international journal of quality of life aspects of 
      treatment, care and rehabilitation
JID - 9210257
SB  - IM
MH  - *Health Status
MH  - *Heart Failure
MH  - Humans
MH  - *Quality of Life
MH  - Reproducibility of Results
MH  - *Surveys and Questionnaires
RF  - 118
EDAT- 2008/12/05 09:00
MHDA- 2009/08/29 09:00
CRDT- 2008/12/05 09:00
PHST- 2007/09/27 00:00 [received]
PHST- 2008/10/24 00:00 [accepted]
PHST- 2008/12/05 09:00 [pubmed]
PHST- 2009/08/29 09:00 [medline]
PHST- 2008/12/05 09:00 [entrez]
AID - 10.1007/s11136-008-9416-4 [doi]
PST - ppublish
SO  - Qual Life Res. 2009 Feb;18(1):71-85. doi: 10.1007/s11136-008-9416-4. Epub 2008 
      Dec 4.