PMID- 19056067
OWN - NLM
STAT- MEDLINE
DCOM- 20090303
LR  - 20110425
IS  - 1875-2136 (Print)
IS  - 1875-2128 (Linking)
VI  - 101
IP  - 10
DP  - 2008 Oct
TI  - What are the differences in presentation of candidates for percutaneous mitral 
      commissurotomy across the world and do they influence the results of the 
      procedure?
PG  - 611-7
LID - 10.1016/j.acvd.2008.09.012 [doi]
AB  - BACKGROUND: Despite marked global differences in the prevalence of rheumatic 
      heart disease, little is known about geographic variations in the characteristics 
      of patients with severe mitral stenosis. AIM: To determine if differences in 
      rheumatic fever epidemiology influence the characteristics of patients with 
      mitral stenosis and the immediate results of percutaneous mitral commissurotomy 
      (PMC). METHODS: We compared 350 patients (mean age: 41+/-17 years, 81% women) 
      scheduled for PMC in five non-Western and two Western countries. Fifty 
      consecutive patients were included in each centre. All presented a mitral valve 
      area less than 1.5 cm2 and were in New York Heart Association (NYHA) functional 
      class greater or equal to II, with no contraindications to PMC. RESULTS: The 250 
      patients from non-Western countries were younger than the 100 patients from 
      Western countries (35+/-12 vs 57+/-15 years, p<0.0001) and had more severe valve 
      disease, assessed by indexed valve area (0.57+/-0.14 vs 0.62+/-0.14 cm2/m2 body 
      surface area, p=0.006), mean gradient (15+/-6 vs 8+/-4 mmHg, p<0.0001) and 
      systolic pulmonary artery pressure (57+/-21 vs 42+/-14 mmHg, p<0.0001). PMC 
      complication rates did not differ significantly. Good immediate PMC results were 
      observed in 225 patients (90%) in non-Western and 88 (88%) in Western centres 
      (p=0.58). CONCLUSIONS: Compared with Western countries, PMC candidates from 
      non-Western countries are younger, with more severe valve stenosis. However, PMC 
      achieves good immediate results in a similarly high proportion of patients, 
      showing the wide applicability of this technique.
FAU - Marijon, Eloi
AU  - Marijon E
AD  - Cardiology Department, Bichat Hospital, AP-HP, 46, rue Henri-Huchard, 75018 
      Paris, France. eloi_marijon@yahoo.fr
FAU - Iung, Bernard
AU  - Iung B
FAU - Mocumbi, Ana-Olga
AU  - Mocumbi AO
FAU - Kamblock, Joel
AU  - Kamblock J
FAU - Thanh, Chien Vo
AU  - Thanh CV
FAU - Gamra, Habib
AU  - Gamra H
FAU - Esteves, Cesar
AU  - Esteves C
FAU - Palacios, Igor F
AU  - Palacios IF
FAU - Vahanian, Alec
AU  - Vahanian A
LA  - eng
PT  - Journal Article
DEP - 20081121
PL  - Netherlands
TA  - Arch Cardiovasc Dis
JT  - Archives of cardiovascular diseases
JID - 101465655
SB  - IM
CIN - Arch Cardiovasc Dis. 2008 Oct;101(10):597-9. PMID: 19056064
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cardiac Surgical Procedures
MH  - Child
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve Stenosis/diagnosis/epidemiology/*surgery
MH  - Rheumatic Heart Disease/epidemiology
MH  - Streptococcal Infections/epidemiology
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2008/12/06 09:00
MHDA- 2009/03/04 09:00
CRDT- 2008/12/06 09:00
PHST- 2008/04/21 00:00 [received]
PHST- 2008/09/09 00:00 [revised]
PHST- 2008/09/09 00:00 [accepted]
PHST- 2008/12/06 09:00 [pubmed]
PHST- 2009/03/04 09:00 [medline]
PHST- 2008/12/06 09:00 [entrez]
AID - S1875-2136(08)00163-0 [pii]
AID - 10.1016/j.acvd.2008.09.012 [doi]
PST - ppublish
SO  - Arch Cardiovasc Dis. 2008 Oct;101(10):611-7. doi: 10.1016/j.acvd.2008.09.012. 
      Epub 2008 Nov 21.