PMID- 19058011
OWN - NLM
STAT- MEDLINE
DCOM- 20090526
LR  - 20090311
IS  - 1572-8781 (Electronic)
IS  - 1387-2176 (Linking)
VI  - 11
IP  - 2
DP  - 2009 Apr
TI  - Effects of strain rate, mixing ratio, and stress-strain definition on the 
      mechanical behavior of the polydimethylsiloxane (PDMS) material as related to its 
      biological applications.
PG  - 503-8
LID - 10.1007/s10544-008-9256-6 [doi]
AB  - Tensile tests on Polydimethylsiloxane (PDMS) materials were conducted to 
      illustrate the effects of mixing ratio, definition of the stress-strain curve, 
      and the strain rate on the elastic modulus and stress-strain curve. PDMS 
      specimens were prepared according to the ASTM standards for elastic materials. 
      Our results indicate that the physiological elastic modulus depends strongly on 
      the definition of the stress-strain curve, mixing ratio, and the strain rate. For 
      various mixing ratios and strain rates, true stress-strain definition results in 
      higher stress and elastic modulus compared with engineering stress-strain and 
      true stress-engineering strain definitions. The elastic modulus increases as the 
      mixing ratio increases up-to 9:1 ratio after which the elastic modulus begins to 
      decrease even as the mixing ratio continues to increase. The results presented in 
      this study will be helpful to assist the design of in vitro experiments to mimic 
      blood flow in arteries and to understand the complex interaction between blood 
      flow and the walls of arteries using PDMS elastomer.
FAU - Khanafer, Khalil
AU  - Khanafer K
AD  - Vascular Mechanics Laboratory, Department of Biomedical Engineering, University 
      of Michigan, Ann Arbor, MI 48109, USA. khanafer@umich.edu
FAU - Duprey, Ambroise
AU  - Duprey A
FAU - Schlicht, Marty
AU  - Schlicht M
FAU - Berguer, Ramon
AU  - Berguer R
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Biomed Microdevices
JT  - Biomedical microdevices
JID - 100887374
RN  - 0 (Biocompatible Materials)
RN  - 0 (Dimethylpolysiloxanes)
RN  - 63148-62-9 (baysilon)
SB  - IM
MH  - Biocompatible Materials/*chemistry
MH  - Computer Simulation
MH  - Dimethylpolysiloxanes/*chemistry
MH  - Elastic Modulus
MH  - *Models, Chemical
MH  - Stress, Mechanical
MH  - Tensile Strength
EDAT- 2008/12/06 09:00
MHDA- 2009/05/27 09:00
CRDT- 2008/12/06 09:00
PHST- 2008/12/06 09:00 [pubmed]
PHST- 2009/05/27 09:00 [medline]
PHST- 2008/12/06 09:00 [entrez]
AID - 10.1007/s10544-008-9256-6 [doi]
PST - ppublish
SO  - Biomed Microdevices. 2009 Apr;11(2):503-8. doi: 10.1007/s10544-008-9256-6.