PMID- 19079903
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20091211
LR  - 20081216
IS  - 1475-2700 (Electronic)
IS  - 0954-4224 (Linking)
VI  - 18
IP  - 2
DP  - 2005 Dec
TI  - A role of vitamin D in low-intensity chronic inflammation and insulin resistance 
      in type 2 diabetes mellitus?
PG  - 175-82
LID - 10.1079/NRR2005104 [doi]
AB  - Evidence from different directions, including observational and experimental 
      studies, points to a role of vitamin D status in low-intensity chronic 
      inflammation and insulin resistance in type 2 diabetes mellitus (T2DM). It has 
      been recognised that insulin resistance and low-intensity chronic inflammation 
      are risk factors for T2DM. Thus, vitamin D status can be implicated in the 
      aetiology of TD2M. It is suggested that the relationship between vitamin D and 
      low-intensity chronic inflammation and insulin resistance in T2DM can be mediated 
      in part by the immune-modulating properties of the active form of vitamin D 
      (1-alpha,25-dihydroxyvitamin D3; 1,25(OH)2D3), which is able to down regulate the 
      production of pro-inflammatory cytokines - particularly TNF-alpha, and IL-6. 
      However, an association between vitamin D status and these features, which is 
      independent of BMI, has been also reported. Non-calcaemic effects of vitaminD can 
      be associated with health outcomes other than those traditionally attributed to 
      the vitamin.
FAU - Flores, Mario
AU  - Flores M
AD  - Centro de Investigacion en Nutricion y Salud, Instituto Nacional de Salud Publica 
      (National Institute of Public Health), Cuernavaca, Mexico. mflores@correo.insp.mx
LA  - eng
PT  - Journal Article
PL  - England
TA  - Nutr Res Rev
JT  - Nutrition research reviews
JID - 9113797
EDAT- 2005/12/01 00:00
MHDA- 2005/12/01 00:01
CRDT- 2008/12/17 09:00
PHST- 2008/12/17 09:00 [entrez]
PHST- 2005/12/01 00:00 [pubmed]
PHST- 2005/12/01 00:01 [medline]
AID - S0954422405000132 [pii]
AID - 10.1079/NRR2005104 [doi]
PST - ppublish
SO  - Nutr Res Rev. 2005 Dec;18(2):175-82. doi: 10.1079/NRR2005104.