PMID- 19091374
OWN - NLM
STAT- MEDLINE
DCOM- 20090318
LR  - 20131121
IS  - 1879-1298 (Electronic)
IS  - 0045-6535 (Linking)
VI  - 74
IP  - 7
DP  - 2009 Feb
TI  - Exposure assessment of persistent organic pollutants and metals in Mexican 
      children.
PG  - 974-80
LID - 10.1016/j.chemosphere.2008.10.030 [doi]
AB  - Environmental policies in Mexico have contributed to the reduction in the 
      production or use of some persistent organic pollutants (POPs) and metals. 
      However, monitoring of POPs concentrations in humans living in hot spots is 
      lacking. Therefore, the objective of this study was to conduct a screening for 
      POPs and metals first in Mexican children living in high-risk areas. During the 
      year 2004, we analyzed a total of 229 healthy children (aged 6-12 years old) who 
      resided in communities located in nine Mexican states. Organochlorine 
      insecticides, PCBs and metals were quantified in plasma and urine samples. We 
      detected p'p-DDE in all the children; moreover, p'p-DDT, lindane and 
      hexachlorobenzene were detected respectively in 14%, 85% and 10% of the children 
      studied. Measurable levels of PCBs were recorded in only one community, where six 
      of 14 PCB congeners assayed were detected (numbers 52, 118, 138, 153, 170 and 
      180). All the children had detectable levels of lead in their blood (mean level, 
      4.6 microg dL(-1)); furthermore, 57% of the children studied had levels higher 
      than 5.0 microg/dL. The mean level of urinary arsenic (UAs) for all the children 
      was 22.35 microg g(-1) creatinine and 15% of those children had concentrations of 
      UAs above 50 microg g(-1) creatinine. For cadmium, the mean urinary level was 
      0.78 microg g(-1) creatinine, and only one percent of the children had values 
      above 2.0 microg g(-1) creatinine. The results cannot be generalized since the 
      communities selected are not representative of the Mexican population; however, 
      they indicate that Mexican children are exposed to chemicals and some at risk 
      levels.
FAU - Trejo-Acevedo, Antonio
AU  - Trejo-Acevedo A
AD  - Departamento de Toxicologia Ambiental, Facultad de Medicina, Universidad Autonoma 
      de San Luis Potosi, Avenida Venustiano Carranza 2405, 78210 San Luis Potosi, 
      S.L.P., Mexico.
FAU - Diaz-Barriga, Fernando
AU  - Diaz-Barriga F
FAU - Carrizales, Leticia
AU  - Carrizales L
FAU - Dominguez, Gabriela
AU  - Dominguez G
FAU - Costilla, Rogelio
AU  - Costilla R
FAU - Ize-Lema, Irina
AU  - Ize-Lema I
FAU - Yarto-Ramirez, Mario
AU  - Yarto-Ramirez M
FAU - Gavilan-Garcia, Arturo
AU  - Gavilan-Garcia A
FAU - Jesus Mejia-Saavedra, J
AU  - Jesus Mejia-Saavedra J
FAU - Perez-Maldonado, Ivan N
AU  - Perez-Maldonado IN
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20081216
PL  - England
TA  - Chemosphere
JT  - Chemosphere
JID - 0320657
RN  - 0 (Environmental Pollutants)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Metals)
RN  - 00BH33GNGH (Cadmium)
RN  - 2P299V784P (Lead)
RN  - N712M78A8G (Arsenic)
SB  - IM
MH  - Arsenic/urine
MH  - Cadmium/urine
MH  - Child
MH  - *Environmental Exposure
MH  - Environmental Pollutants/*analysis/blood/urine
MH  - Humans
MH  - Hydrocarbons, Chlorinated/*analysis/blood/urine
MH  - Lead/blood
MH  - Metals/*analysis/blood/urine
MH  - Mexico
EDAT- 2008/12/19 09:00
MHDA- 2009/03/19 09:00
CRDT- 2008/12/19 09:00
PHST- 2008/03/26 00:00 [received]
PHST- 2008/07/22 00:00 [revised]
PHST- 2008/10/05 00:00 [accepted]
PHST- 2008/12/19 09:00 [entrez]
PHST- 2008/12/19 09:00 [pubmed]
PHST- 2009/03/19 09:00 [medline]
AID - S0045-6535(08)01282-4 [pii]
AID - 10.1016/j.chemosphere.2008.10.030 [doi]
PST - ppublish
SO  - Chemosphere. 2009 Feb;74(7):974-80. doi: 10.1016/j.chemosphere.2008.10.030. Epub 
      2008 Dec 16.