PMID- 19092569
OWN - NLM
STAT- MEDLINE
DCOM- 20090326
LR  - 20131121
IS  - 1535-1815 (Electronic)
IS  - 0749-5161 (Linking)
VI  - 24
IP  - 12
DP  - 2008 Dec
TI  - Management of anaphylaxis in children.
PG  - 861-6; quiz 867-9
LID - 10.1097/PEC.0b013e31818ea116 [doi]
AB  - Anaphylaxis is a severe, life-threatening immunoglobulin E (IgE)-mediated 
      hypersensitivity reaction. The key to successful management of anaphylaxis 
      involves rapid diagnosis, assessment, and early initiation of therapy. 
      Epinephrine is the undisputed initial therapy for anaphylaxis, and its 
      administration should never be delayed. In most cases, additional interventions 
      such as oxygen therapy, fluid resuscitation, beta-agonists, antihistamines, and 
      corticosteroids should be strongly considered. Although hospital course must be 
      individualized to meet each patient's needs, a minimum of 4 to 6 hours of 
      observation period after complete symptom resolution may be reasonable to monitor 
      for recurrence of symptoms and biphasic reaction. Before discharge, every patient 
      should receive patient education about anaphylaxis, a prescription for 
      self-injectable epinephrine, and instructions for follow-up care.
FAU - Liberman, Danica B
AU  - Liberman DB
AD  - Division of Emergency Medicine, Children's National Medical Center, Washington, 
      DC 20010, USA. dliberma@cnmc.org
FAU - Teach, Stephen J
AU  - Teach SJ
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Pediatr Emerg Care
JT  - Pediatric emergency care
JID - 8507560
RN  - 0 (Adrenal Cortex Hormones)
RN  - 0 (Bronchodilator Agents)
RN  - 0 (Histamine Antagonists)
RN  - 0 (Vasoconstrictor Agents)
RN  - 9007-92-5 (Glucagon)
RN  - QF8SVZ843E (Albuterol)
RN  - YKH834O4BH (Epinephrine)
SB  - IM
EIN - Pediatr Emerg Care. 2009 Feb;25(2):77
MH  - Adrenal Cortex Hormones/therapeutic use
MH  - Albuterol/therapeutic use
MH  - Anaphylaxis/diagnosis/drug therapy/*therapy
MH  - Bronchodilator Agents/therapeutic use
MH  - Child
MH  - Child, Preschool
MH  - Combined Modality Therapy
MH  - Disease Management
MH  - Early Diagnosis
MH  - Emergencies
MH  - Emergency Service, Hospital
MH  - Epinephrine/administration & dosage/therapeutic use
MH  - Female
MH  - First Aid
MH  - Fluid Therapy
MH  - Glucagon/therapeutic use
MH  - Histamine Antagonists/therapeutic use
MH  - Humans
MH  - Infant
MH  - Male
MH  - Oxygen Inhalation Therapy
MH  - Vasoconstrictor Agents/therapeutic use
RF  - 21
EDAT- 2008/12/19 09:00
MHDA- 2009/03/27 09:00
CRDT- 2008/12/19 09:00
PHST- 2008/12/19 09:00 [entrez]
PHST- 2008/12/19 09:00 [pubmed]
PHST- 2009/03/27 09:00 [medline]
AID - 00006565-200812000-00014 [pii]
AID - 10.1097/PEC.0b013e31818ea116 [doi]
PST - ppublish
SO  - Pediatr Emerg Care. 2008 Dec;24(12):861-6; quiz 867-9. doi: 
      10.1097/PEC.0b013e31818ea116.