PMID- 19100402
OWN - NLM
STAT- MEDLINE
DCOM- 20090225
LR  - 20081222
IS  - 0041-1345 (Print)
IS  - 0041-1345 (Linking)
VI  - 40
IP  - 10
DP  - 2008 Dec
TI  - Outcome after renal transplantation in a "senior" program: the Croatian 
      experience.
PG  - 3418-21
LID - 10.1016/j.transproceed.2008.06.109 [doi]
AB  - BACKGROUND: The Eurotransplant "senior" program allocates kidneys from elderly 
      donors to patients >65 years old. It aims to increase the number of renal 
      transplantations. Kidneys are allocated locally without human leukocyte antigen 
      (HLA) matching to decrease the cold ischemia time. Croatia has introduced its own 
      "senior" program based on HLA matching. We compared results with those from 
      Eurotransplant. METHODS: We identified and prospectively followed all patients 
      aged of >or=65 years who underwent a first renal transplantation. We recorded 
      their HLA matching, cold ischemia time, renal function, surgical and medical 
      complications, and duration of hospitalization. RESULTS: Through October 2007, 22 
      elderly patients received an allograft from donors who were >65 years old. There 
      were 8 female and 14 male patients of mean age at transplantation of 67.4 years. 
      Mean donor age was 66 years. The number of HLA mismatches ranged from 1 to 5, and 
      cold ischemia time from 7 to 15 hours. One-year patient survival was 95.4%, and 
      graft survival was 81.8%. Delayed graft function, defined as the need for 
      dialysis for >7 days after transplantation, occurred in 63.6% of patients. Older 
      recipients required prolonged hospitalization after transplantation (45 days; 
      range, 16-131). Frequent posttransplant complications included posttransplant 
      diabetes mellitus in 1 patient, delayed wound healing in 5 patients, and 
      lymphocoel in 2 patients. Maligancies occurred in 3 patients, neoplasm of the 
      native kidney, posttransplant lymphoproliferative disease, and skin cancer. One 
      patient experienced acute rejection that was successfully treated with steroids. 
      Seventeen patients experienced 20 viral infections. There was only 1 serious 
      infection (pulmonary tuberculosis). The major problems were cardiovascular 
      complications which occurred in 40.9% of patients.
FAU - Basic-Jukic, N
AU  - Basic-Jukic N
AD  - Department of Dialysis, UHC Zagreb, Zagreb, Croatia.
FAU - Furic-Cunko, V
AU  - Furic-Cunko V
FAU - Kes, P
AU  - Kes P
FAU - Bubic-Filipi, L
AU  - Bubic-Filipi L
FAU - Pasini, J
AU  - Pasini J
FAU - Hudolin, T
AU  - Hudolin T
FAU - Juric, I
AU  - Juric I
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Transplant Proc
JT  - Transplantation proceedings
JID - 0243532
SB  - IM
MH  - Aged
MH  - Body Mass Index
MH  - Croatia
MH  - Diabetes Mellitus/epidemiology
MH  - Europe
MH  - Female
MH  - Humans
MH  - Kidney Transplantation/adverse effects/*physiology
MH  - Length of Stay
MH  - Male
MH  - Postoperative Complications/epidemiology
MH  - Prospective Studies
MH  - Renal Replacement Therapy/statistics & numerical data
MH  - Treatment Outcome
EDAT- 2008/12/23 09:00
MHDA- 2009/02/26 09:00
CRDT- 2008/12/23 09:00
PHST- 2008/02/11 00:00 [received]
PHST- 2008/06/13 00:00 [revised]
PHST- 2008/06/18 00:00 [accepted]
PHST- 2008/12/23 09:00 [entrez]
PHST- 2008/12/23 09:00 [pubmed]
PHST- 2009/02/26 09:00 [medline]
AID - S0041-1345(08)01214-1 [pii]
AID - 10.1016/j.transproceed.2008.06.109 [doi]
PST - ppublish
SO  - Transplant Proc. 2008 Dec;40(10):3418-21. doi: 
      10.1016/j.transproceed.2008.06.109.