PMID- 19101853
OWN - NLM
STAT- MEDLINE
DCOM- 20091014
LR  - 20091117
IS  - 1747-7174 (Electronic)
IS  - 1747-7166 (Linking)
VI  - 4
IP  - 3
DP  - 2009
TI  - Cardiovascular disease risk factor (CVDRF) associated waist circumference 
      patterns in obese-prone children.
PG  - 150-9
LID - 10.1080/17477160802596130 [doi]
AB  - OBJECTIVES: The present study tested whether children born at high risk (HR) 
      compared with low risk (LR) for obesity are more likely to have a waist 
      circumference (WC) associated with cardiovascular disease risk factors (CVDRF-WC) 
      and tested whether CVDRF-WC status tracks over time. METHODS: This prospective 
      cohort study involved 71 children, three to eight years, who were divided into 
      two groups, LR (n = 37) and HR (n = 34), based upon maternal prepregnancy body 
      mass index (BMI). HR subjects were subdivided into HR normal-weight (HRNW) and HR 
      overweight (HROW) groups, based on BMI > or = 85%. Children were classified as 
      having or not having a CVDRF-WC at each year, using age- and gender-specific WC 
      cut-offs. Anthropometry was assessed annually. RESULTS: Although HR children had 
      a significantly greater mean WC than LR children at years 5-8 (p < 0.03), these 
      differences became non-significant after adjusting for BMI. HROW were more likely 
      to have a CVDRF-WC status (p < or = 0.0001) at age 4 years (10%, 5%, vs. 58%), 5 
      years (3%, 10%, vs. 60%), 6 years (0%, 0%, vs. 70%), 7 years (0%, 0%, vs. 50%) to 
      8 years (0%, 0%, vs. 55%) than LR and HRNW. Although 60-100% of the children 
      tracked CVDRF-WC status, higher proportions of HROW children (0-40%) transitioned 
      into having a CVDRF-WC, compared with LR (0-6%) and HRNW (0-9%). CONCLUSIONS: 
      HROW were more likely to have or develop a CVDRF-WC. Although the effects of 
      obesity risk on WC may be secondary to BMI, clinically assessing WC in 
      obese-prone children may help identify youth at risk for obesity-related 
      complications.
FAU - Leibowitz, Karen L
AU  - Leibowitz KL
AD  - The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104-4399, 
      USA. peddm@aol.com
FAU - Moore, Renee H
AU  - Moore RH
FAU - Stunkard, Albert J
AU  - Stunkard AJ
FAU - Stallings, Virginia A
AU  - Stallings VA
FAU - Berkowitz, Robert I
AU  - Berkowitz RI
FAU - Stettler, Nicolas
AU  - Stettler N
FAU - Chittams, Jesse L
AU  - Chittams JL
FAU - Faith, Myles S
AU  - Faith MS
LA  - eng
GR  - DK068899/DK/NIDDK NIH HHS/United States
GR  - RR00240/RR/NCRR NIH HHS/United States
GR  - UL1-RR-024134/RR/NCRR NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Int J Pediatr Obes
JT  - International journal of pediatric obesity : IJPO : an official journal of the 
      International Association for the Study of Obesity
JID - 101256330
SB  - IM
MH  - Body Mass Index
MH  - Cardiovascular Diseases/*etiology
MH  - Child
MH  - Child, Preschool
MH  - Humans
MH  - Obesity/*etiology
MH  - Risk Factors
MH  - *Waist Circumference
EDAT- 2008/12/23 09:00
MHDA- 2009/10/15 06:00
CRDT- 2008/12/23 09:00
PHST- 2008/12/23 09:00 [entrez]
PHST- 2008/12/23 09:00 [pubmed]
PHST- 2009/10/15 06:00 [medline]
AID - 907070250 [pii]
AID - 10.1080/17477160802596130 [doi]
PST - ppublish
SO  - Int J Pediatr Obes. 2009;4(3):150-9. doi: 10.1080/17477160802596130.