PMID- 19109097
OWN - NLM
STAT- MEDLINE
DCOM- 20090212
LR  - 20191111
IS  - 1121-760X (Print)
IS  - 1121-760X (Linking)
VI  - 52
IP  - 4
DP  - 2008 Oct-Dec
TI  - Identification of orexin A- and orexin type 2 receptor-positive cells in the 
      gastrointestinal tract of neonatal dogs.
PG  - 229-35
AB  - The presence and distribution of cells positive to orexin A (OXA) and to orexin 
      type 2 receptor (OX2R) were investigated in the gastrointestinal tract of 
      neonatal dogs by means of immunohistochemical techniques. The orexin A-positive 
      cells were identified with some of the endocrine cells in the stomach and in the 
      duodenum; they were both of the open and closed type and were lacking in the 
      large intestine. In the stomach, a large subset of orexin A-positive cells also 
      showed gastrin-like immunoreactivity while, in the duodenum, many of them seemed 
      to store serotonin. The orexin type 2 receptor-positive cells were evidenced all 
      along the gastrointestinal tract examined, also in the large intestine, and they 
      showed the same morphological characteristics as those positive to orexin A. 
      Moreover, the immunohistochemical techniques revealed intense positivity for both 
      orexin A and orexin type 2 receptor in the neurons and fibers of the enteric 
      nervous system. A large subset of orexin A-positive neurons seemed to store 
      substance P.
FAU - Dall'Aglio, C
AU  - Dall'Aglio C
AD  - Dipartimento di Scienze Biopatologiche Veterinarie ed Igiene delle Produzioni 
      Animali ed Alimentari, Sezione di Anatomia Veterinaria, Via San Costanzo 4, 
      06126, Perugia, Italy. cecilia.dallaglio@unipg.it
FAU - Pascucci, L
AU  - Pascucci L
FAU - Mercati, F
AU  - Mercati F
FAU - Giontella, A
AU  - Giontella A
FAU - Pedini, V
AU  - Pedini V
FAU - Scocco, P
AU  - Scocco P
FAU - Ceccarelli, P
AU  - Ceccarelli P
LA  - eng
PT  - Journal Article
PL  - Italy
TA  - Eur J Histochem
JT  - European journal of histochemistry : EJH
JID - 9207930
RN  - 0 (Intracellular Signaling Peptides and Proteins)
RN  - 0 (Neuropeptides)
RN  - 0 (Orexin Receptors)
RN  - 0 (Orexins)
RN  - 0 (Receptors, G-Protein-Coupled)
RN  - 0 (Receptors, Neuropeptide)
SB  - IM
MH  - Animals
MH  - Animals, Newborn
MH  - Cell Count
MH  - Dogs/anatomy & histology/*physiology
MH  - Duodenum/cytology/*metabolism
MH  - Enteroendocrine Cells/cytology/*metabolism
MH  - Female
MH  - Gastric Mucosa/*metabolism
MH  - Immunohistochemistry
MH  - Intracellular Signaling Peptides and Proteins/*metabolism
MH  - Male
MH  - Neuropeptides/*metabolism
MH  - Orexin Receptors
MH  - Orexins
MH  - Receptors, G-Protein-Coupled/*metabolism
MH  - Receptors, Neuropeptide/*metabolism
MH  - Stomach/cytology
EDAT- 2008/12/26 09:00
MHDA- 2009/02/13 09:00
CRDT- 2008/12/26 09:00
PHST- 2008/12/26 09:00 [entrez]
PHST- 2008/12/26 09:00 [pubmed]
PHST- 2009/02/13 09:00 [medline]
AID - 10.4081/1221 [doi]
PST - ppublish
SO  - Eur J Histochem. 2008 Oct-Dec;52(4):229-35. doi: 10.4081/1221.